Abstract The electrode for the neural interface is the place where the independent systems of engineering and biology interact electrically for communication. It is a unidirectional or bidirectional channel through…
Abstract The dorsal root ganglion (DRG) is a unique neural structure in the nervous system as it not only houses the somata of the primary sensory neurons (PSNs) but also…
Abstract Deep brain stimulation (DBS) was first used to treat essential tremor and the movement disorders associated with Parkinson disease. Its success led to its consideration as treatment for a…
Abstract There has been a steady increase in the amount of published data on the mechanism of action (MOA) of vagus nerve stimulation (VNS) in the past 2 decades, but…
Abstract Neuromodulation elicited by electrical stimulation of peripheral or spinal nerves is a US Food and Drug Administration–approved therapy for treating several disorders of the pelvic viscera. Although the detailed…
Abstract Burst stimulation was developed based on a very simple principle that mimicking naturally occurring firing patterns might be beneficial for neuromodulation. Its main benefit lies in the capacity of…
Abstract Spinal cord stimulation (SCS) has been used in managing chronic pain conditions that are refractory to current pharmacotherapies. However, conventional SCS has often been associated with suboptimal efficacy and…
Abstract Surgeons, neurologists, researchers, and patients have lacked the technology-based tools to facilitate sharing the tremendously valuable data about patients’ treatment and research in regard to what is working and…
Abstract The safe delivery of electrical currents for the stimulation of neural tissue requires careful consideration of stimulus intensities to avoid tissue and electrode damage. This chapter discusses charge density…
Abstract Advances in magnetic resonance imaging (MRI) are revolutionizing our understanding of brain structure and function. The integration of this technology in patients with neuromodulation devices raises some compatibility and…
