Third-Generation Antiepileptic Drugs
28 CHAPTER Third-Generation Antiepileptic Drugs Cesar C. Santos The U.S. Food and Drug Administration (FDA) approved the third-generation antiepileptic drugs (AEDs) between 2004 and 2012. The AEDs included in this…
Status Epilepticus and Frequent Nonconvulsive Seizures
34 CHAPTER Status Epilepticus and Frequent Nonconvulsive Seizures Keith E. Dombrowski Status epilepticus (SE), particularly generalized convulsive status epilepticus (GCSE), is a common problem encountered in the United States and…
Ambulatory EEG
13 CHAPTER Ambulatory EEG Robbie D. Buechler Ambulatory electroencephalography (AEEG) is a monitoring technique that allows the recording of continuous EEG (cEEG) activity when patients are at home. This obviates…
Psychiatric Comorbidities
38 CHAPTER Psychiatric Comorbidities Sarah K. Rivelli Approximately half of all patients with epilepsy have psychiatric symptoms or disorders. Psychiatric comorbidity is an important predictor of health and quality of…
First-Generation Antiepileptic Drugs
26 CHAPTER First-Generation Antiepileptic Drugs José E. Cavazos The first-generation antiepileptic drugs (AEDs), often known as traditional AEDs, marked a significant advance in epilepsy therapy. Before the introduction of phenobarbital,…
Stimulation Therapy
30 CHAPTER Stimulation Therapy William B. Gallentine Despite the addition of numerous new antiepileptic drugs (AEDs) over the past 20 years, a substantial number of patients with epilepsy (approximately 35%)…
Pathophysiology
1 CHAPTER Pathophysiology Cheolsu Shin The past decade has seen an explosion of the discovery of various genetic causes of many diseases, including epilepsy. With the rapid technological development in…
Newest Antiepileptic Drugs and Drugs in Development
29 CHAPTER Newest Antiepileptic Drugs and Drugs in Development K. Nicole Mims and Aatif M. Husain Despite the approval of many new antiepileptic drugs (AEDs) in the past 20 years,…
EMU Safety Concerns
44 CHAPTER EMU Safety Concerns Susan Hollar and Deborah LaBelle-Scarfo There are a variety of challenges, details, and protocols associated with epilepsy monitoring unit (EMU) admissions. While any inpatient admission…
