Congenital Myopathies
Chapter 93 Congenital Myopathies Jonathan B. Strober The congenital myopathies are a group of disorders characterized by their histopathologic findings on muscle biopsy. A prevalence of 3.5–5/10,000 children has been…
Pediatric Epilepsy: An Overview
Chapter 50 Pediatric Epilepsy An Overview Peter R. Camfield, Carol S. Camfield After a first unprovoked seizure in childhood, the risk of a recurrence is about 50 percent, and after…
Introduction to Genetics
Chapter 30 Introduction to Genetics William B. Dobyns, Susan L. Christian, Soma Das In the broadest sense, genes are simply units of hereditary information; the genome is the totality of…
Disorders of Neural Tube Development
Chapter 22 Disorders of Neural Tube Development Nalin Gupta, M. Elizabeth Ross Introduction Neural tube defects (NTDs) are among the most frequently encountered congenital anomalies involving the central nervous system…
Neurologic Disorders in Children with Heart Disease
Chapter 101 Neurologic Disorders in Children with Heart Disease Catherine Limperopoulos, Adré J. du Plessis Introduction Neurologic disorders are among the most common complications in children with heart disease. The…
Hypoxic-Ischemic Encephalopathy in Infants and Older Children
Chapter 76 Hypoxic-Ischemic Encephalopathy in Infants and Older Children Ronald M. Perkin, Stephen Ashwal Cardiac arrest in childhood is often a catastrophic event that is associated with mortality or poor…
Neurologic Examination of the Term and Preterm Infant
Chapter 4 Neurologic Examination of the Term and Preterm Infant Kenneth F. Swaiman The Term Infant Fetal monitoring during the labor process is difficult, but certain variables can be studied….
Cognitive and Motor Regression
Chapter 44 Cognitive and Motor Regression David J. Michelson, Stanford K. Shu Introduction Diseases in which there is a gradual loss of cognitive function can be described as progressive encephalopathies…
Muscular Dystrophies
Chapter 92 Muscular Dystrophies Diana M. Escolar, Robert T. Leshner Introduction Muscular dystrophies are progressive, inherited skeletal muscle disorders resulting in muscle degeneration and loss of strength. This heterogeneous group…
Disorders of Cerebellar and Brainstem Development
Chapter 24 Disorders of Cerebellar and Brainstem Development Kathleen J. Millen, Joseph G. Gleeson A number of newly described syndromes and diseases now allow for careful consideration of cerebellar and…
