Pregnancy pregnancy
Is a normal vaginal delivery safe? Can a spinal or epidural anaesthetic be used? Are any offspring likely to be affected as well? 15.2 Pathophysiology Symptoms of Chiari develop as…
Clinical Presentation
Fig. 8.1 Origin of symptoms. This flowchart illustrates how both the syrinx and its underlying pathology combine to produce a variety of neurological symptoms (Courtesy of Graham Flint) 8.5 Differential…
Historical Aspects
Fig. 1.1 Title page of Stephanus ’ De dissectione partium corporis humani (1545) (Courtesy History & Special Collections for the Sciences, Louise M. Darling Biomedical Library, University of California, Los…
Genetics of Chiari Malformation and Syringomyelia
Proposed inheritance Number of families Affected members Reference study Autosomal dominant with reduced penetrance 21 families Parent–child, siblings, avuncular pairsa, cousins Milhorat et al. (1999) 23 families Parent–child, siblings, avuncular…
