Fig. 8.1 Unadjusted predicted probability of mortality and favorable outcome at 90 days by onset-to-reperfusion time. Solid line represents the probability of outcome (gray, all-cause mortality; black, favorable outcome) over…
Author Year Urokinase/streptokinase/plasmin animal model Main results (compared with controls when applicable) Whisnant [78] 1960 Clot in Internal Carotid Artery No increased risk of hemorrhagic infarction compared with controls Centero…
Author (ref.) N Thrombolytic agent Ancillary Outcome Herndona [11, 12, 14] 27 Fibrinolysin over 3 d iv Heparin, Dicoumarol 15 % involved, 33 % died, 4 systemic hemorrhages Clarke [4]…
rt-PA (%) Placebo (%) Odds ratio (95 % CI) P value Global test 1.7 (1.2–2.6) 0.008 Barthel Index 50 38 1.6 (1.1–2.5) 0.026 mRS 39 26 1.7 (1.1–2.5) 0.019…
