Molecular Biology Primer for Neurosurgeons
CHAPTER 3 Molecular Biology Primer for Neurosurgeons Kevin Y. Miyashiro, James Eberwine Commenting on the structure and connections of neurons during his acceptance speech for the Nobel Prize in Medicine,…
Animal Models of Epilepsy
CHAPTER 50 Animal Models of Epilepsy Maria Elisa Calcagnotto, Scott C. Baraban Epilepsy affects a sizable proportion of the population worldwide and is responsible for a heavy social and economic…
Epilepsy Surgery Overview
CHAPTER 48 Epilepsy Surgery Overview Guy M. McKhann, II, Matthew A. Howard, III Neurological surgery has played an important role in the management of patients with epilepsy throughout the history…
Blood-Brain Barrier
CHAPTER 8 Blood-Brain Barrier Shahid M. Nimjee, Gerald A. Grant, H. Richard Winn, Damir Janigro The blood-brain barrier (BBB) is a “neurovascular unit” composed of microvascular endothelium, basement membrane, neurons,…
Cerebral Edema
CHAPTER 9 Cerebral Edema Robert J. Weil, Edward H. Oldfield Overview and Historical Background Cerebral edema represents the accumulation of excess fluid in the intracellular or extracellular spaces of the…
Neuroanesthesia
CHAPTER 21 Neuroanesthesia Preoperative Evaluation Deepak Sharma, Arthur M. Lam The neuroanesthesiologist’s goals can be divided into three periods—the preoperative period: (1) prepare the patient and family for the planned…
Surgical Planning
CHAPTER 25 Surgical Planning Overview Martin Weiss, Gabriel Zada, Alexander A. Khalessi Comprehensive planning represents an axiomatic prerequisite for any neurosurgical procedure. “Failing to prepare is preparing to fail” holds…
Intracranial Pressure Monitoring
CHAPTER 23 Intracranial Pressure Monitoring Vincent Y. Wang, Geoffrey T. Manley Historical Perspective The importance of intracranial pressure (ICP) was first recognized by Alexander Monro more than 200 years ago…
Neuropsychological Testing
CHAPTER 16 Neuropsychological Testing Jordan Grafman Neuropsychological testing as practiced by neuropsychologists is an important, some might say necessary, adjunct to most neurosurgical practices. Neuropsychology has both a clinical and…
Stem Cell Biology in the Central Nervous System
CHAPTER 5 Stem Cell Biology in the Central Nervous System Philip J. Horner, Samuel E. Nutt In a series of papers published in the 1960s, Joseph Altman and colleagues reported…
