Atlas of Pathologic Substrates of Epilepsy Richard A. Prayson Ajay Gupta Figure 1.1 Low-magnification appearance of hippocampus in a patient with hippocampal sclerosis (HS). An adult patient who underwent anterior…
Electroencephalographic Atlas of Epileptiform Abnormalities Soheyl Noachtar Elaine Wyllie Electroencephalography (EEG) is generally considered the single most important laboratory tool in the evaluation of patients with epilepsy. This atlas of…
Application of Electroencephalography in the Diagnosis of Epilepsy David R. Chabolla Gregory D. Cascino The electroencephalogram (EEG) is the most frequently performed neurodiagnostic study in patients with a seizure disorder…
Neurophysiologic Basis of the Electroencephalogram Erwin-Josef Speckmann Christian E. Elger Ulrich Altrup Field potentials appear and are detectable in the space surrounding cellular elements of the nervous system. They comprise…
The Natural History of Seizures W. Allen Hauser Descriptive epidemiologic studies provide information about the frequency of epilepsy and other convulsive disorders in the population. Individuals identified in these cohorts…
Epidemiologic Aspects of Epilepsy Anne T. Berg Until the 1960s, the prevailing view about epilepsy was captured by the words of Sir William Gowers: “The tendency of the disease is…
Genetics Aspects of Epilepsy and Genetics of Idiopathic Generalized Epilepsy Ajay Gupta Ingrid E. Scheffer Epilepsy, defined by the recurrence of unprovoked seizures, is a complex disorder. Complex inheritance refers…
Mechanisms of Epileptogenesis and Experimental Models of Seizures Imad Najm Gabriel Möddel Damir Janigro The term epileptogenesis refers to abnormal firing of neurons sufficient to produce episodic epileptiform electrophysiologic activity…
Basic Cellular Neurophysiology Stephen W. Jones ION CHANNELS AND INTRINSIC MEMBRANE PROPERTIES Basis of Electrical Activity The activity of ion channels is fundamental to signaling in the nervous system. Synaptic…
Human Nervous System Development and Malformations Harvey B. Sarnat Laura Flores-Sarnat Development of the brain, both normal and abnormal, is the result of genetically determined events that occur sequentially but…
