Fig. 7.1 An overview of isolation methods and characteristics of early and late EPCs 7.2.4 Classification of EPCs According to their culture characteristics and functions, circulation EPCs can be classified…
Fig. 2.1 Schematic diagram of NSC/NPC behavior in the RMS. a NSC/NPC behavior in the RMS of intact brain. Note that NSCs/NPCs in the RMS are divided into two sub-types:…
Fig. 4.1 BMSC therapy induces neurorestorative effects post stroke Fig. 4.2 The various aspects of neurorestoration that are targeted by cell therapy to improve neurological recovery post stroke 4.3.1 BMSC…
© Springer International Publishing Switzerland 2015Li-Ru Zhao and John H. Zhang (eds.)Cellular Therapy for Stroke and CNS InjuriesSpringer Series in Translational Stroke Research10.1007/978-3-319-11481-1_3 3. The Role of Endogenous Neural Stem Cells in Stroke Qichuan ZhuGe1, 3 ,…
Fig. 15.1 Pathophysiological time course following TBI. (Reproduced from Walker et al. [32]) Extracellular matrix destabilization occurs along with cellular dysfunction. The concentration of several matrix metalloproteinase (MMP) proteins are…
Study reference/principal investigator Study title Route Cell type/source Recipient species Therapeutic window Dose Outcome measures Follow-up/outcome measurements Results summary [10] Treatment of stroke in rat with intracarotid administration of marrow…
Study Phase Type of cells Route of injection Time after stroke Sample size Results Kondziolka et al., Neurology 2000 I Cultured neuronal cells differentiated from a human teratocarcinoma cell line…
Fig. 10.1 iNSC functioning as a cell-replacement therapy and as a producer of regenerative therapeutics for stroke patients. a A patient who has an ischemic or hemorrhagic stroke (ischemic stroke…
Fig. 1.1 Depiction of the three therapeutic approaches to acute brain injury. (Note that devices also have potential from clot-retrieval devices to devices that stimulate the sphenopalatine ganglia to blood…
Fig. 4.1 Change in the strategy for stroke. a Treatment of cardiovascular factors and administration of antiplatelet/coagulant drugs significantly contribute to the prevention of stroke onset. b In addition to…
