Medication adherence Adverse effects/intolerance Adequate treatment duration Outcome definition (improvement/response/remission) Inclusion of non-antidepressant concomitant treatments Phenocopies/medical comorbidity Comparison groups for TRD cohort A related problem is the range of medical…
Gene Function Polymorphism(s) Main finding(s) Clinical applications References SLC6A4 Serotonin transporter 5-HTTLPR S allele worse response in Caucasians treated with SSRIs and higher risk of SSRI-induced side effects Included in…
Author Subjects Treatment Brain areas Results Vakili et al. [100] 38 patients (17 males, mean age 38.5 ± 10.0 years) 20 healthy controls (9 males, mean age 40.3 ± 10.4 years) Fluoxetine, 20 mg/day…
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