Chapter 7 – Functional Connectome in Bipolar Disorder
Abstract Bipolar disorder (BD) is a major psychiatric illness which is thought to have strong biological underpinnings. A biological basis for BD is exemplified by a strong heritability of the…
Chapter 6 – Resting-State Functional Connectivity in Unipolar Depression
Abstract Unipolar depression, also known as unipolar or major depressive disorder (MDD), is a globally prevalent psychiatric disorder characterized by persistent sadness and a loss of interest in normally enjoyable…
Chapter 5 – Brain Imaging of Reward Dysfunction in Unipolar and Bipolar Disorders
Abstract In recent years, there has been tremendous support for working toward the RDoC goals of identifying the neurobiological mechanisms that cut across or are common to multiple psychiatric disorders….
Chapter 4 – Neuroimaging Biomarkers in Pediatric Mood Disorders
Abstract Mood disorders, including bipolar disorder (BD) and major depressive disorder (MDD), are serious and often-recurring psychiatric conditions that commonly first manifest during childhood or adolescence (1, 2). Youth with…
Chapter 3 – Neuroanatomical Findings in Bipolar Disorder
Abstract Over the past three decades, numerous cross-sectional neuroimaging studies have reported neuroanatomical abnormalities in patients with bipolar disorder compared with healthy volunteers. These studies have highlighted those anatomical regions…
Chapter 2 – Neuroanatomical Findings in Unipolar Depression and the Role of the Hippocampus
Abstract Depressive disorders are common conditions with a life prevalence of 15% in high-income countries (1) and significant economic implications for individuals and society. Major depressive disorders have negative repercussions…
Chapter 1 – Brain Imaging Methods in Mood Disorders
Abstract Mood disorders are the most common mental illnesses with a lifetime prevalence of up to 20% worldwide (1). Major depressive disorder (MDD) and bipolar disorder (BD) are significant health…
Case 34 – Concerns about the Future
Abstract A 65-year-old accountant presented to the consultation to investigate whether her memory lapses are the first manifestations of Fahr’s disease. She noticed, during the last few years, a progressive…
Case 33 – Young Woman with Problems Concentrating
Abstract Ms. L is having a regular ongoing follow-up with a psychiatrist in private practice for a history of bipolar disorder (BP). She reported a first major depressive episode at…
Case 32 – Left or Right: Which Way to Go?
Abstract A 73-year-old Brazilian, right-handed man, retired business manager, began having progressively cognitive and behavioral disorders for the past 5 years. His family noticed some behavioral changes, as he presented…
