Increased Intracranial Pressure
The presenting complaint when dealing with increased intracranial pressure ( Box 4-1 ) varies with age. Infants may present with bulging fontanelle, macrocephaly or failure to thrive. Older children often…
NEUROLOGY
Altered States of Consciousness
The terms used to describe states of decreased consciousness are listed in Table 2-1 . With the exception of coma, these definitions are not standard. However, they are more precise…
Paroxysmal Disorders
Paroxysmal disorders are characterized by the sudden onset of neurological dysfunction and stereotyped recurrence. In children, such events often clear completely. Examples of paroxysmal disorders include epilepsy, migraine, periodic paralysis,…
Brain Metastasis after Prophylactic Cranial Irradiation in Patients with Small Cell Lung Cancer
Keywords brain metastases, small cell lung cancer, prophylactic cranial irradiation, chemotherapy, relapse rate, detection, management Outline Introduction 200 Brain Metastasis after Prophylactic Cranial Irradiation 201 How Often does Brain…
Multiple Small Brain Metastases with Limited Focal Brain Edema from Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Mutations
Keywords brain metastases, non-small cell lung cancer, EGFR mutations, epidermal growth factor receptor tyrosine-kinase inhibitors, treatment, gefitinib, erlotinib Outline Introduction 106 Epidermal Growth Factor Receptor Mutations 106 Multiple Brain…
Lambert–Eaton Myesthenic Syndrome and Brain Metastasis from Occult Small Cell Lung Carcinoma: A Clinician’s Perspective
Keywords brain metastasis, small cell lung cancer, Lambert–Eaton myasthenic syndrome, autoimmune Outline Introduction 244 Lambert–Eaton Myesthenic Syndrome 244 Paraneoplastic and Non-Paraneoplastic LEMS 244 Pathophysiology 245 Clinical Features 245 Investigations…
Brain Metastasis from Small-Cell Lung Cancer with High Levels of Placental Growth Factor
Keywords brain metastases, small cell lung cancer, placental growth factor, blood–brain barrier, tight junctions, brain endothelial cells Outline Introduction 213 Placental Growth Factor 215 Placental Growth Factor in Normal…
Radiation Management of Synchronous Brain Metastases from Non-Small Cell Lung Cancer
Keywords brain metastases, non-small cell lung cancer, surgical resection, stereotactic radiosurgery, whole brain radiotherapy Outline Introduction 182 Management of Brain Metastases in Patients with NSCLC 182 General Considerations for…
Brain Metastases from Lung Cancer
Keywords brain metastases, lung cancer, surgical resection, stereotactic radiosurgery, whole brain radiation therapy, prophylactic cranial radiation, toxicity Outline Introduction 227 Treatment Options 228 Surgical Resection 228 Stereotactic Radiosurgery 228…
