Blood–Brain Barrier Disruption
Chapter 12 Blood–Brain Barrier Disruption Abstract The blood–brain barrier (BBB) is a dynamic system that separates the peripheral blood from the neural tissue. It is composed of endothelial cells connected…
Gliotransmitters
Chapter 3 Gliotransmitters Abstract Glial cells were classically thought of passive “glue” that held neurons together. This view was challenged, however, with the use of new techniques, most notably patch-clamp…
Gap Junctions
Chapter 11 Gap Junctions Abstract Electrotonic coupling between cells is accomplished through the formation of gap junctions (GJs) between cells. Composed of connexin proteins, GJs are found on multiple cell…
Therapeutic Targets and Future Directions
Chapter 14 Therapeutic Targets and Future Directions Abstract As astrocytes are the elements of the nervous system responsible for homeostatic function, and disease represents loss of homeostasis, therapeutic targets for…
