Figure 5.1 Axial T2-weighted fluid-attenuated inversion recovery (FLAIR) scans of a 56-year-old patient affected by nfvPPA, showing an enlargement of the left lateral ventricle and the frontal subarachnoid spaces bilaterally,…
Figure 2.1 Final pathologies, first syndrome, and subsequent evolution through second and third syndromes in patients from our center presenting initially with bvFTD. Aphasia developing secondarily is indicated as progressive…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 1 Historical introduction to FTD John R. Hodges Hodges’ Frontotemporal Dementia, Second Edition, ed. Bradford C. Dickerson. Published by Cambridge University Press. © Cambridge University…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 3 Overview of frontotemporal dementia and the variety of its clinical presentations Matthew Jones and David Neary Hodges’ Frontotemporal Dementia, Second Edition, ed. Bradford C….
Figure 16.1 Schematic diagram showing activities of daily living (ADLs) subclassified into basic (Basic ADLs) and instrumental (Instrumental ADLs). The assessment of functional abilities should be included in clinical investigations…
Figure 13.1 Relative frequency of major molecular pathologic subtypes of frontotemporal lobar degeneration (FTLD). FET, fused in sarcoma, Ewing’s sarcoma, TATA-binding protein-associated factor 15 family of proteins; tau, microtubule-associated protein…
Figure 10.1 Regional brain atrophy across three clinical stages of behavioral variant FTD. In the group with very mild dementia (CDR 0.5), atrophy involved areas in the frontal lobe (rostromedial…
Figure 8.1 The complexity of clinicopathologic relationships along the frontotemporal lobar degeneration (FTLD) spectrum. The major clinical syndromes along the FTLD spectrum are shown in the top row of the…
MAPT (tau)GRN (progranulin)TDP-43TauOthersVCPCHMP2BTARDBP (TDP-43)FUSFUS C9ORF72 C9ORF72 is the newest addition to the roster of causative molecules in FTD. In 2011, expansions of a GGGGCC hexanucleotide repeat in C9orf72 were found…
Figure 9.1 The INECO Frontal Screening (IFS) [39]. Classical executive function tests The most frequent classical executive function tests used in patients with bvFTD are: the backward digit span [5],…
