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Introduction At the turn of the twentieth century, Dr. Alois Alzheimer described a form of progressive presenile dementia in a female patient named Auguste Deter, who developed memory loss and…
Chapter 1: Introduction Elizabeth Heada,*; Mark Mapstoneb; Ira T. Lottb,c a Department of Pathology & Laboratory Medicine, University of California, Irvine, CA, United Statesb Department of Neurology, University of California, Irvine,…
Genetics of oxidative stress in Down syndrome Growing studies support the hypothesis that oxidative stress (OS) contributes to neurodevelopmental defects, neuronal dysfunction, as well as the accelerated aging phenotype of…
