Closed-Loop Responsive Stimulation for Epilepsy
Abstract The first edition of Neuromodulation was published in 2009, 4 years prior to the approval of the responsive neurostimulation system (RNS) by the United States Food and Drug Administration….
NEUROLOGY
Deep Brain Stimulation for Obsessive–Compulsive Disorder
Abstract Obsessive–compulsive disorder (OCD) is a psychiatric disorder characterized by persistent obsessions with intrusive thoughts leading to severe generalized anxiety and/or compulsions in the form of repetitive tasks to relieve…
Vagal Nerve Simulation
Abstract Vagus nerve stimulation (VNS) is a safe and reliable treatment adjunct for patients with medically intractable epilepsy. It is both a preventive and an abortive form of therapy, effective…
Epilepsy : Anatomy, Physiology, Pathophysiology, and Disorders
Abstract Epilepsy is one of the top three most prevalent neurological disorders worldwide, together with headache and cerebrovascular diseases. Epilepsy is defined as a disease of the brain characterized by…
Deep Brain Stimulation of the Pedunculopontine Tegmental Nucleus Improves Static Balance in Parkinson’s Disease
Abstract Postural instability is a major problem in Parkinson’s disease (PD), being poorly responsive to l -dopa treatment. There is now hope that deep brain stimulation (DBS) of the pedunculopontine…
Infusion Therapy for Movement Disorders
Abstract Direct intracerebral infusion of neurotrophic factors may represent a neuroprotective and neurorestorative therapeutic strategy for neurodegenerative movement disorders, most notably Parkinson’s disease (PD). The significant majority of past research…
Neuromodulation for Headaches—Sphenopalatine Ganglion Stimulation
Abstract The sphenopalatine ganglion (SPG), also called the pterygopalatine ganglion, is the switching station for the final common pathway for cluster headache, may serve as the final synapse in the…
Surgical Management of Hemifacial Spasm and Meige Syndrome
Abstract Most people experience trivial movements of their facial muscles during daily life. These are often barely recognizable, but they sometimes imply pathological conditions that require appropriate treatments. Hemifacial spasm…
Deep Brain Stimulation in Tourette Syndrome
Abstract Tourette syndrome (TS) is a chronic neuropsychiatric disorder with an unknown etiology characterized by motor and vocal tics. The onset of tics occurs most commonly in early childhood around…
Deep Brain Stimulation for Dystonia
Abstract Dystonia is etiologically classified as primary versus secondary based on the absence or presence, respectively, of an identifiable underlying cause. Deep brain stimulation (DBS) at the internal globus pallidus…
