Mechanical Revascularization with Embolectomy Devices
Fig. 7.1 Clinical specimens from mechanical thrombectomy in acute stroke demonstrating: (a) the fibrin rich clot or so-called white clot, and (b) the red blood cell rich clot, termed red…
NEUROLOGY
The Ischemic Penumbra and Cell Survival
Fig. 1.1 (a) Traditional concept that the infarct core is surrounded by an enveloping penumbra. (b) Alternative concept that regions corresponding to core and penumbra may be heterogeneous Ischemic heterogeneity…
Combination of Thrombolytic Therapy with Antithrombotics and Neuroprotectants
Fig.3.1 Percentage of patients achieving any recanalization (as detected by transcranial doppler ultrasound or CT angiography) within 2 h of tPA bolus, complete recanalization 2 h after tPA bolus, reocclusion…
How to Run an Effective Code Stroke
Key elements Advantages Composition—EMS, emergency medicine, neurology, surgery, radiology, nursing Diversity of talent and knowledge across medical center High visibility and availability 24/7 to evaluate acute stroke victims Stroke awareness…
The rt-PA for Acute Stroke Protocol
Site Sponsor Contents Links to other sites? http://www.brainattackcoalition.org/ Brain Attack Coalition Protocols, Scales, Guidelines, Sample Orders, Consensus Statements Yes; very complete, very simple to use www.stroke.org/ National Stroke Association Protocols,…
Telestroke: Delivery and Design
© Springer International Publishing Switzerland 2015Patrick D Lyden (ed.)Thrombolytic Therapy for Acute Stroke10.1007/978-3-319-07575-4_11 11. Telestroke: Delivery and Design Konrad H. Schlick1 and Brett C. Meyer2 (1) Department of Neurosciences, UCSD School of Medicine, 200 W. Arbor Drive, MON…
Intra-arterial Thrombolysis in Acute Ischemic Stroke
Fig. 6.1 (a) Illustration of microcatheter placement into an MCA clot. (b) Angiogram demonstrating acute occlusion of the M1 segment of the MCA (arrow). (c) Recanalized MCA after 600,000 U…
Thrombolytic Therapy for Acute Stroke and the Test of Time
Fig. 9.1 These bars illustrate the NIHSS and Barthel Index results for 49 patients greater than age 75 and presenting with NIHSS greater than 22 before treatment (Adapted from Subgroup…
Combination of Intravenous t-PA and Endovascular Therapy
Fig. 8.1 Unadjusted predicted probability of mortality and favorable outcome at 90 days by onset-to-reperfusion time. Solid line represents the probability of outcome (gray, all-cause mortality; black, favorable outcome) over…
The March of Thrombolytic Therapy for Acute Ischemic Stroke to Clinical Trials: Pre-clinical Thrombolysis and Adjuncts to Thrombolysis Research
Author Year Urokinase/streptokinase/plasmin animal model Main results (compared with controls when applicable) Whisnant [78] 1960 Clot in Internal Carotid Artery No increased risk of hemorrhagic infarction compared with controls Centero…
