The Art of the Clinical Trial
Chapter 210 The Art of the Clinical Trial Zoher Ghogawala, Robert G. Whitmore The purpose of the clinical trial is to determine the safety, efficacy, and/or effectiveness of a medical…
Deformity Surgery for Ankylosing Spondylitis
Chapter 99 Deformity Surgery for Ankylosing Spondylitis J. Patrick Johnson, Darren L. Bergey, Michael Weisman, Robert S. Pashman Ankylosing spondylitis (AS) is an inflammatory disease that can lead to painful…
Stereotactic Radiosurgery for the Treatment of Spinal Metastases
Chapter 176 Stereotactic Radiosurgery for the Treatment of Spinal Metastases John H. Shin, Lilyana Angelov Metastatic tumors are the most common tumors affecting the spinal column and are the cause…
Arachnoiditis
Chapter 196 Arachnoiditis Robert F. Heary, Antonios Mammis Spinal arachnoiditis is a nonspecific inflammatory process of the arachnoid layer of the spinal cord or cauda equina. Arachnoiditis was first described…
Penetrating Spinal Cord Injuries
Chapter 73 Penetrating Spinal Cord Injuries Michael P. Steinmetz, William McCormick, Alex Valadka, Perry A. Ball, Philip A. Yazbak, Edward C. Benzel Penetrating spine injury is a major cause of…
Chiari Malformations and Syringomyelia
Chapter 119 Chiari Malformations and Syringomyelia Samuel R. Browd, Richard Ellenbogen Chiari malformations are commonly encountered in both pediatric and adult neurosurgical practices. Multiple variations in the anatomic development of…
Upper Cervical and Occipitocervical Arthrodesis
Chapter 38 Upper Cervical and Occipitocervical Arthrodesis M. Yashar, S. Kalani, Udaya K. Kakarla, Volker K.H. Sonntag, Nicholas Theodore The cervicomedullary junction (CMJ) is a challenging region in which to…
Somatosensory-Evoked Potential for Spine Surgery
Chapter 177 Somatosensory-Evoked Potential for Spine Surgery Virgilio Matheus, Jorge A. Gonzalez-Martinez, Dileep Nair Because degenerative spinal conditions and deformities are relatively prevalent, surgical procedures for the spine are common….
The Geriatric Patient
Chapter 131 The Geriatric Patient Robert A. Hart, Mark D. D’Alise, Edward C. Benzel When planning either elective or emergent spinal surgery in elderly patients, the numerous physiologic changes associated…
Smoking and the Spine
Chapter 130 Smoking and the Spine David W. Schippert, Glenn R. Rechtine, II Tobacco is responsible for one in five deaths, and tobacco use is the single largest preventable cause…
