The neurobiology of psychopathy: recent developments and new directions in research and treatment

Mar 19, 2017 by in PSYCHIATRY Comments Off on The neurobiology of psychopathy: recent developments and new directions in research and treatment

Interest in understanding psychopathy continued from the nineteenth century into the twentieth century. Based on interviews conducted with hundreds of prisoners, Cleckley formed a narrative conceptualization and description of psychopathic…

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California State Hospital Violence Assessment and Treatment (Cal-VAT) guidelines

Mar 19, 2017 by in PSYCHIATRY Comments Off on California State Hospital Violence Assessment and Treatment (Cal-VAT) guidelines

Figure 16.1 Treatment algorithm for acute agitation. Table 16.1 Dosing recommendations: conventional antipsychotics Medication (brand) Recommended dose range High-dosing recommendations Recommended plasma concentration Long-acting depot recommendations Chlorpromazine (Thorazine) 300–1000 mg/day…

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Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy

Mar 19, 2017 by in PSYCHIATRY Comments Off on Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy

Figure 21.1 Antipsychotic treatment algorithm. Following several unsuccessful atypical antipsychotic monotherapy trials, a trial with a conventional antipsychotic or with clozapine is recommended. High-dose monotherapy may also be considered for…

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Deconstructing violence as a medical syndrome: mapping psychotic, impulsive, and predatory subtypes to malfunctioning brain circuits

Mar 19, 2017 by in PSYCHIATRY Comments Off on Deconstructing violence as a medical syndrome: mapping psychotic, impulsive, and predatory subtypes to malfunctioning brain circuits

Figure 9.1 Heterogeneity of aggression. Identifying the type of aggression a patient is displaying may help guide the selection of appropriate treatments that target the underlying dysfunctional circuits. However, violence…

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Psychosocial approaches to violence and aggression: contextually anchored and trauma-informed interventions

Mar 19, 2017 by in PSYCHIATRY Comments Off on Psychosocial approaches to violence and aggression: contextually anchored and trauma-informed interventions

Figure 28.1 SAMHSA components and principles of recovery for individuals and organizations. Trauma-Informed Perspective There is growing recognition that trauma is widespread, and that the experience of trauma has far-reaching…

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A rational approach to employing high plasma levels of antipsychotics for violence associated with schizophrenia: case vignettes

Mar 19, 2017 by in PSYCHIATRY Comments Off on A rational approach to employing high plasma levels of antipsychotics for violence associated with schizophrenia: case vignettes

Figure 22.1 Relationship between plasma fluphenazine levels and estimated probability of improvement (gray line) and disabling side effects (black line) [20]. Figure 22.2 The relationship between plasma haloperidol and the…

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Serotonin and impulsive aggression

Mar 19, 2017 by in PSYCHIATRY Comments Off on Serotonin and impulsive aggression

Figure 15.1a Amygdala BOLD responses to social threat (angry faces) before and after 12 weeks of treatment with placebo (n = 10) vs. fluoxetine (n = 3) or divalproex (n…

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