Introduction

Sep 12, 2021 by in NEUROLOGY Comments Off on Introduction

Chapter 1: Introduction Elizabeth Heada,*; Mark Mapstoneb; Ira T. Lottb,c    a Department of Pathology & Laboratory Medicine, University of California, Irvine, CA, United Statesb Department of Neurology, University of California, Irvine,…

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Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer’s dysmetabolism, neuropathology, and possible therapies

Sep 12, 2021 by in NEUROLOGY Comments Off on Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer’s dysmetabolism, neuropathology, and possible therapies

Genetics of oxidative stress in Down syndrome Growing studies support the hypothesis that oxidative stress (OS) contributes to neurodevelopmental defects, neuronal dysfunction, as well as the accelerated aging phenotype of…

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Future directions

Sep 12, 2021 by in NEUROLOGY Comments Off on Future directions

Keywords Biomarkers; Cerebrovascular; Clinical trials; Genetics; Neuroimaging; Neuropathology; Neuropsychology Two decades ago, if charged with the task of indicating future directions for research into Down syndrome (DS) and Alzheimer’s disease…

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