Chapter 36 Melatonin and the Regulation of Sleep and Circadian Rhythms Béatrice Guardiola-Lemaître, Maria Antonia Quera-Salva Abstract Biological functions are organized according to time-dependent cycles (circadian; i.e., 24 hours, and…
Chapter 13 Genetics of Sleep in a Simple Model Organism Drosophila Ravi Allada Abstract The complexity of sleep in mammals has led to a movement toward examining simpler model systems,…
Chapter 44 Wake-Promoting Medications Basic Mechanisms and Pharmacology Seiji Nishino, Emmanuel Mignot Abstract Central nervous system stimulants currently used in sleep medicine include amphetamine-like compounds (L– and D-amphetamine, L– and…
Chapter 57 Cardinal Manifestations of Sleep Disorders Bradley V. Vaughn, O’Neill F. D’Cruz Abstract Sleep disorders include a wide range of disorders that impair health and quality of life. Clinicians…
Chapter 41 Circadian Disorders of the Sleep–Wake Cycle Kathryn J. Reid, Phyllis C. Zee Abstract Circadian rhythm sleep disorders (CRSD) are primarily due to alterations of the circadian time-keeping system…
Chapter 135 Insomnia in Older Adults Sonia Ancoli-Israel, Tamar Shochat, Abstract Insomnia is a complaint of difficulty initiating or maintaining sleep or of nonrestorative sleep resulting in significant daytime consequences….
Chapter 148 Gastrointestinal Monitoring Techniques William C. Orr, Chien Lin Chen Abstract Symptoms suggesting unexplained arousals from sleep resulting in complaints of insomnia or daytime sleepiness may well have nocturnal…
Chapter 89 Sleep and Neuromuscular Diseases Michelle T. Cao, Charles F.P. George, Christian Guilleminault Abstract Neuromuscular disorders consist of central and peripheral neurologic disorders with impairment of the motor system….
Chapter 83 Treatment Guidelines for Insomnia Michael J. Sateia, Daniel J. Buysse Abstract Treatment guidelines are evidence and consensus-based recommendations that are intended to guide clinical practice. Guidelines are particularly…
