aAfter administration of eslicarbazepine acetate. CYP, Cytochrome P450; UGT, UDP-glucuronosyltransferase; NAT, N-acetyltransferase; nk, not known. Figure 44.1. Relationship between pharmacokinetics and pharmacodynamics. PHARMACOKINETIC PARAMETERS Absorption Absorption refers to the passage…
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Figure 85.1. Proposed algorithm for the evaluation of patients with multilobar and multilesional epilepsy. The algorithm departs from the findings in the brain MRI. The first element to consider is…
Figure 62.1. Rufinamide. MW 238.2, (C10H8F2N4O). Rufinamide is nearly insoluble in water and slightly soluble in methanol and ethanol. This would make it difficult to prepare an intravenous formulation. Solubility…
Figure 19.1. EEG–EMG recording with surface electrodes in a 3-year-old boy with MAE (Doose syndrome). Three brief and symmetric myoclonic jerks each time-locked to single generalized single spike–wave discharges are…
Table 27.2 Tumor Types Encountered in Medically Intractable, Chronic Epilepsy using Data Retrieved from the European Epilepsy Brain Bank Table 27.3 Seizure Frequency in Various Brain Tumor Types CLINICAL CHARACTERISTICS…
aAvoid concomitant use with the lowest dose oral contraceptive pills, and additional nonhormonal forms of contraception should be used. PREGNANCY Epilepsy is the most common neurologic disorder that requires continuous…
Related posts: The Natural History of Seizures Hormones, Catamenial Epilepsy, Sexual Function, and Reproductive and Bone Health in Epilepsy Epilepsy in the Setting of Inherited Metabolic and Mitochondrial Disorders Phenobarbital…
To address the above issues, the International League Against Epilepsy (ILAE) issued a commission report proposing a new outcome classification scheme (Table 90.2). Completely seizure-free patients are classified separately; seizures…
