NEUROLOGY
Surgical Approach in Multilesional or Multilobar Epilepsies
Figure 85.1. Proposed algorithm for the evaluation of patients with multilobar and multilesional epilepsy. The algorithm departs from the findings in the brain MRI. The first element to consider is…
Rufinamide
Figure 62.1. Rufinamide. MW 238.2, (C10H8F2N4O). Rufinamide is nearly insoluble in water and slightly soluble in methanol and ethanol. This would make it difficult to prepare an intravenous formulation. Solubility…
Progressive and Infantile Myoclonic Epilepsies
Figure 19.1. EEG–EMG recording with surface electrodes in a 3-year-old boy with MAE (Doose syndrome). Three brief and symmetric myoclonic jerks each time-locked to single generalized single spike–wave discharges are…
Brain Tumors and Epilepsy
Table 27.2 Tumor Types Encountered in Medically Intractable, Chronic Epilepsy using Data Retrieved from the European Epilepsy Brain Bank Table 27.3 Seizure Frequency in Various Brain Tumor Types CLINICAL CHARACTERISTICS…
Treatment of Epilepsy During Pregnancy
aAvoid concomitant use with the lowest dose oral contraceptive pills, and additional nonhormonal forms of contraception should be used. PREGNANCY Epilepsy is the most common neurologic disorder that requires continuous…
Outcome and Complications of Epilepsy Surgery
To address the above issues, the International League Against Epilepsy (ILAE) issued a commission report proposing a new outcome classification scheme (Table 90.2). Completely seizure-free patients are classified separately; seizures…
Benzodiazepines
Figure 50.1. Structure of the 1,4-benzodiazepines. Substituents at the named sites are given in the table for diazepam, lorazepam, clonazepam, nitrazepam, and clorazepate. Midazolam with its fused R1 ring is…
