NEUROLOGY

Intraoperative Microelectrode Recording

Sep 24, 2016 by in NEUROLOGY Comments Off on Intraoperative Microelectrode Recording

Fig. 4.1 Electrodes used for microelectrode recording (MER). (a) MER performed using the electrode tip (arrowhead) as the recording electrode and the tip of the outer sheath (arrow) as the…

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Surgical Technique of Brain Stimulation

Sep 24, 2016 by in NEUROLOGY Comments Off on Surgical Technique of Brain Stimulation

and Toru Itakura2 (1) Department of Neurological Surgery, Wakayama Medical University Hospital, Wakayama, Japan (2) Department of Neurological Surgery, Koyo Hospital, Wakayama, Japan   6.1 Introduction Deep brain stimulation (DBS) is…

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Functional Circuitry of the Basal Ganglia

Sep 24, 2016 by in NEUROLOGY Comments Off on Functional Circuitry of the Basal Ganglia

Fig. 1.1 Basal ganglia. Human basal ganglia shown in a frontal section and in a lateral view (inset). The basal ganglia receive cortical inputs and return processed information to the…

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Complications of Deep Brain Stimulation

Sep 24, 2016 by in NEUROLOGY Comments Off on Complications of Deep Brain Stimulation

  Complications related to surgical procedure Intracranial hemorrhage Epilepsy Air embolism Follett KA n = 299 2 – – Deuschl G n = 78 3.8 – – Kleiner-Fisman G n = 921 3.9 1.5 – PahwaR…

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Deep Brain Stimulation for Epilepsy: Evidence for Limbic Network Disruption via Chronic Anterior Nucleus of the Thalamus and Hippocampus Stimulation

Sep 24, 2016 by in NEUROLOGY Comments Off on Deep Brain Stimulation for Epilepsy: Evidence for Limbic Network Disruption via Chronic Anterior Nucleus of the Thalamus and Hippocampus Stimulation

Study Type No. of patients Seizure type Follow up Stimulation parameters Resultsa SANTE Multi-center, double-blind, randomized controlled trial 108 Partial onset 3 months (blinded) 145 Hz, 1 min on, 5…

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Mechanism of DBS: Inhibition, Excitation, or Disruption?

Sep 24, 2016 by in NEUROLOGY Comments Off on Mechanism of DBS: Inhibition, Excitation, or Disruption?

Fig. 2.1 Proposed mechanism underling effectiveness of deep brain stimulation (DBS). DBS dissociates input and output signals in the stimulated nucleus, resulting in disruption of abnormal information flow through the…

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Deep Brain Stimulation for Psychiatric Disorders

Sep 24, 2016 by in NEUROLOGY Comments Off on Deep Brain Stimulation for Psychiatric Disorders

Fig. 13.1 Clinical trials in deep brain stimulation, according to the National Institute of Health (NIH) clinical trials registry (From Lozano and Lipsman (2013) with permission) 13.2 MDD 13.2.1 Epidemiology…

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