Chapter 9 Atypical parkinsonism, parkinsonism-plus syndromes, and secondary parkinsonian disorders Chapter contents Introduction 197 Progressive supranuclear palsy 197 Multiple system atrophy 208 Corticobasal degeneration 218 Parkinsonism–dementia syndromes 222 Frontotemporal dementias…
Chapter 6 Medical treatment of Parkinson disease Chapter contents Introduction 119 Therapeutic principles 119 Therapeutic choices available for Parkinson disease 121 Medications available for Parkinson disease 121 Treatment of early-stage…
Chapter 19 The tardive syndromes Phenomenology, concepts on pathophysiology and treatment, and other neuroleptic-induced syndromes Chapter contents Overview 415 Fundamentals and definitions 416 Dopamine receptors and their antagonists 418 “Atypical”…
Chapter 10 Gait disorders Pathophysiology and clinical syndromes Chapter contents Balance 241 Gait 242 Gait disorders 244 Therapeutic considerations 249 Gait is a fundamental skill. It permits movement from place…
Chapter 14 Huntington disease Chapter contents Introduction 311 Epidemiology 311 Clinical aspects 311 Natural course 314 Neuroimaging 315 Neuropathology and neurochemistry 316 Genetics 318 Pathogenesis 322 Treatment 326 Experimental therapeutics…
Chapter 22 The paroxysmal dyskinesias Chapter contents Introduction 476 Definitions: transient, paroxysmal, episodic, and periodic 477 Historical aspects 477 Classification of the paroxysmal dyskinesias 482 Paroxysmal kinesigenic dyskinesia (PKD) 483…
Chapter 4 Parkinsonism Clinical features and differential diagnosis Chapter contents Introduction 66 Clinical features 66 Bradykinesia 69 Tremor 69 Rigidity and flexed posture 70 Loss of postural reflexes 71 Freezing…
Chapter 7 Surgical treatment of Parkinson disease and other movement disorders Chapter contents Introduction 157 Functional anatomy of the basal ganglia 157 Techniques of stereotactic surgery 159 Thalamotomy 160 Ablative…
Chapter 15 Chorea, ballism, and athetosis Chapter contents Introduction 335 Dentatorubral-pallidoluysian atrophy and HD-like disorders 335 Other Huntington disease-like disorders 337 Neuroacanthocytosis 339 Neurodegeneration with brain iron accumulation 341 Other…
