Autoimmune and Postinfectious Diseases
Autoimmune and Postinfectious Diseases Agustín Legido Silvia N. Tenembaum Christos D. Katsetos John H. Menkes This chapter considers several groups of neurologic diseases believed to result from a failure of…
Infections of the Nervous System
Infections of the Nervous System Bernard L. Maria James F. Bale Jr. Many different pathogens can invade and damage the developing or mature central nervous system (CNS). These infectious disorders…
Perinatal Asphyxia and Trauma
Perinatal Asphyxia and Trauma John H. Menkes Harvey B. Sarnat The name “cerebral palsy” is thus nothing other than an invented word, the product of our nosographic classification, a label…
Malformations of the Central Nervous System
Malformations of the Central Nervous System John H. Menkes Harvey B. Sarnat Laura Flores-Sarnat Malformations of the brain and spinal cord may be genetically determined or acquired. The great majority…
The New Neuroembryology
The New Neuroembryology Harvey B. Sarnat Preformation is represented by DNA, not by … a tiny adult in every sperm. —Antonio García-Bellido, 1998 (1) Traditional embryology is descriptive morphogenesis: detailed…
Chromosomal Anomalies and Contiguous-Gene Syndromes
Chromosomal Anomalies and Contiguous-Gene Syndromes John H. Menkes Rena E. Falk This chapter considers conditions that develop as a result of chromosomal abnormalities. Abnormalities of chromosomes are either constitutional or…
Heredodegenerative Diseases
Heredodegenerative Diseases John H. Menkes Advances in molecular biology have pointed to a basic similarity between diseases of metabolic origin (see Chapter 1) and heredodegenerative diseases. Nevertheless, essential differences remain….
Inherited Metabolic Diseases of the Nervous System
Inherited Metabolic Diseases of the Nervous System John H. Menkes William R. Wilcox The diseases considered in this chapter result from a single mutant gene that codes for an enzymatic…
Mitochondrial Encephalomyopathies
Mitochondrial Encephalomyopathies Harvey B. Sarnat John H. Menkes Mitochondrial disease may cause any symptom in any tissue at any age by any inheritance. —A. Munnich The above definition of mitochondrial…
Introduction: Neurologic Examination of the Child and Infant
Introduction: Neurologic Examination of the Child and Infant John H. Menkes Franklin G. Moser The ever-increasing sophistication and accuracy of neurodiagnostic procedures might cause younger physicians to view the neurologic…
