Chronic Immune Sensory Polyneuropathy Responding to Immunotherapy
Figure 47-1 Nerve conduction studies before (A and B) and after 18 months of treatment (C). A, Nerve conduction study of left tibial nerve. Conduction block with 80% reduction after…
Meningeal Enhancement in POEMS Syndrome: Another Clinical Sign of Vascular Endothelial Growth Factor Overactivity?
Figure 56-1 A and B, T1-weighted magnetic resonance imaging scan with gadolinium demonstrates diffuse pachymeningeal enhancement. The patient has a history of hypertension, probable coronary artery disease, and previous episodes…
Copper Deficiency Myeloneuropathy
Figure 51-1 Zinc toxicity and copper deficiency: Excretion of copper into the gastrointestinal tract is the major pathway that regulates copper homeostasis and prevents deficiency or toxicity. Excessive zinc ingestion…
Gait Imbalance, Urinary Urgency, and Mild Cognitive Dysfunction – A Case of Adult Polyglucosan Body Disease
Figure 29-1 T1-weighted sagittal magnetic resonance imaging (MRI) scan of the cranicervical junction (left) showing marked atrophy of the entire spinal cord without associated signal abnormality, and T2-weighted sagittal MRI…
Length-Related Axonal Loss in Neuropathy
Figure 72-1 The chest wall of the patient described had normal pinprick sensibility near the spine, but posterior to the posterior axillary line, she had blunted sensation to pinprick (region…
A Weak, and Numb Patient with Tremor—Antimyelin-Associated Glycoprotein Polyneuropathy
Figure 46-1 Higher power view of sural nerve biopsy, transverse semithin section, stained with toluidine blue demonstrating loss of myelinated axons, thinly myelinated axons, a circumferentially oriented Schwann cell profile…
How Far Have We Come in Prevention and Treatment of Peripheral Neuropathy?
CHAPTER 71 How Far Have We Come in Prevention and Treatment of Peripheral Neuropathy? Peter J. Dyck, MD INTRODUCTION At a recent conference assessing “Advances in understanding and treating neuropathy”…
Inflammatory Multifocal Encephalomyelopolyradiculoneuropathy Mimicking a Granulomatous or Lymphomatous Process
Multiple cerebrospinal fluid (CSF) analyses showed consistently high protein levels (maximum 1250 mg/dL) and cell counts (maximum 250 white blood cells, 89% lymphocytes) but no malignant cells (Table 5-2). Table…
Acute Paraplegia—Saddle Embolism of Abdominal Aorta
Figure 17-1 The serial nerve conduction studies of the left peroneal motor nerve (A) and the right tibial motor nerve (B) in acute stage: upper trace, the initial study which…
A Case of Guillain-Barré Syndrome Associated with Anti-GD1b Immunoglobulin G Antibodies
Autoantibodies to gangliosides By an enzyme-linked immunosorbent assay (ELISA) as described elsewhere,1 IgM and IgG antibodies against ganglioside GM1, GM1b, GD1a, GalNAc-GD1a, GD1b, GT1a, or GQ1b were investigated in serum…
