Intra-arterial Thrombolysis in Acute Ischemic Stroke
Fig. 6.1 (a) Illustration of microcatheter placement into an MCA clot. (b) Angiogram demonstrating acute occlusion of the M1 segment of the MCA (arrow). (c) Recanalized MCA after 600,000 U…
Thrombolytic Therapy for Acute Stroke and the Test of Time
Fig. 9.1 These bars illustrate the NIHSS and Barthel Index results for 49 patients greater than age 75 and presenting with NIHSS greater than 22 before treatment (Adapted from Subgroup…
Combination of Intravenous t-PA and Endovascular Therapy
Fig. 8.1 Unadjusted predicted probability of mortality and favorable outcome at 90 days by onset-to-reperfusion time. Solid line represents the probability of outcome (gray, all-cause mortality; black, favorable outcome) over…
The March of Thrombolytic Therapy for Acute Ischemic Stroke to Clinical Trials: Pre-clinical Thrombolysis and Adjuncts to Thrombolysis Research
Author Year Urokinase/streptokinase/plasmin animal model Main results (compared with controls when applicable) Whisnant [78] 1960 Clot in Internal Carotid Artery No increased risk of hemorrhagic infarction compared with controls Centero…
Pilot and Preliminary Studies of Thrombolytic Therapy for Stroke
Author (ref.) N Thrombolytic agent Ancillary Outcome Herndona [11, 12, 14] 27 Fibrinolysin over 3 d iv Heparin, Dicoumarol 15 % involved, 33 % died, 4 systemic hemorrhages Clarke [4]…
Intravenous Thrombolytic Therapy for Acute Ischemic Stroke: Results of Large, Randomized Clinical Trials
rt-PA (%) Placebo (%) Odds ratio (95 % CI) P value Global test 1.7 (1.2–2.6) 0.008 Barthel Index 50 38 1.6 (1.1–2.5) 0.026 mRS 39 26 1.7 (1.1–2.5) 0.019…
Clinical Magnetic Resonance Neuroimaging in Mild Cognitive Impairment and Alzheimer Disease
Fig. 28.1 Positioning of a single-voxel in the bilateral posteromedial parietal cortex for study with frontal, sagittal, and axial slices. The area explored includes the posterior cingulate gyrus To date,…
The Role of Iron and Other Trace Elements on Mental Development and Cognitive Function
Fig. 12.1 Minerals and trace elements: relationship with cognition, brain function, Parkinson and Alzheimer disease and other diseases such as Friedreich ataxia Consideration should be taken into account regarding…
Biological Markers in Psychiatry and Its Relation with Translational Approaches: Brief Historical Review
Fig. 23.1 Comparative graphic of the amphetamine and phenethylamine molecules. Note the similarity of the molecular structure Other groups have reported a reduction in phenylacetic acid levels measured in urine,…
Learning Styles: From Basic Investigation to Learning in the Classroom
Fig. 16.1 Visual and acoustic avoidance conditioning. Bars represent the percentages of conditioned avoidance responses for 50 trials. The values are the mean ± SEM. of 8–10 animals on each group. For…
