28 CHAPTER Third-Generation Antiepileptic Drugs Cesar C. Santos The U.S. Food and Drug Administration (FDA) approved the third-generation antiepileptic drugs (AEDs) between 2004 and 2012. The AEDs included in this…
34 CHAPTER Status Epilepticus and Frequent Nonconvulsive Seizures Keith E. Dombrowski Status epilepticus (SE), particularly generalized convulsive status epilepticus (GCSE), is a common problem encountered in the United States and…
13 CHAPTER Ambulatory EEG Robbie D. Buechler Ambulatory electroencephalography (AEEG) is a monitoring technique that allows the recording of continuous EEG (cEEG) activity when patients are at home. This obviates…
38 CHAPTER Psychiatric Comorbidities Sarah K. Rivelli Approximately half of all patients with epilepsy have psychiatric symptoms or disorders. Psychiatric comorbidity is an important predictor of health and quality of…
26 CHAPTER First-Generation Antiepileptic Drugs José E. Cavazos The first-generation antiepileptic drugs (AEDs), often known as traditional AEDs, marked a significant advance in epilepsy therapy. Before the introduction of phenobarbital,…
30 CHAPTER Stimulation Therapy William B. Gallentine Despite the addition of numerous new antiepileptic drugs (AEDs) over the past 20 years, a substantial number of patients with epilepsy (approximately 35%)…
1 CHAPTER Pathophysiology Cheolsu Shin The past decade has seen an explosion of the discovery of various genetic causes of many diseases, including epilepsy. With the rapid technological development in…
29 CHAPTER Newest Antiepileptic Drugs and Drugs in Development K. Nicole Mims and Aatif M. Husain Despite the approval of many new antiepileptic drugs (AEDs) in the past 20 years,…
44 CHAPTER EMU Safety Concerns Susan Hollar and Deborah LaBelle-Scarfo There are a variety of challenges, details, and protocols associated with epilepsy monitoring unit (EMU) admissions. While any inpatient admission…
41 CHAPTER Epilepsy and Headaches Timothy A. Collins Epilepsy and migraine have been discussed as having possible links since the late 1800s. In 1906, Gowers gave a series of lectures…
