Characteristics* Total number of patients 21 Sex Male 6 (29) Female 15 (71) Male/female rate 0.4 Mean age (years) 52.8 ± 16.5 Range (years) 19–78 Presentation Unruptured 9 (43) Ruptured 12 (57)…
Fig. 1 OxyHb and HB-EGF suppressed K V currents of cerebral artery myocytes from control animals but not from SAH model animals. (a) Example of whole-cell K+ currents before and…
Fig. 1 Modified Garcia Score at 24 and 48 h (maximum score of 18). The SAH group had significantly lower modified Garcia Scores at both 24 and 48 h compared…
Fig. 1 Third intervention for patient No. 5; DSA anterior/posterior projection. Note the typical additional effect on vasodilation of milrinone supplementary to nimpodipine (orange arrow M1 segment, yellow arrow A1…
Inclusion criteria Exclusion criteria Age ≥ 18 years old Nonaneurysmal hemorrhage Confirmed aSAH Unstable clinical condition Aneurysm secured (clipping or coiling) Aneurysm not secured (clipping or coiling) WFNS grade 1 or 2…
Fig. 1 Histogram of documented cerebral vasospasm. The greatest frequency of vasospasm was during days 11–14 (5 of 7 patients) Fig. 2 Changes in the metal cation concentration in the…
Fig. 1 Post SAH patient mortality and underlying mechanisms: mortality in SAH patients is greatest in the early phase (a). Although early mortality results from early activating mechanisms, delayed mortality…
Fig. 1 The kinetics of Hb (a) and haptoglobin (b) levels in CSF after SAH Our previous study had suggested intrathecal soluble CD163 shedding after SAH [6], which may partially…
Fig. 1 TRPV4 inhibition does not alter the amplitude or frequency of spontaneous Ca2+ events in astrocyte endfeet after SAH. (a) Spontaneous Ca2+ oscillations recorded from 1.2 × 1.2-μm regions of interest…
© Springer International Publishing Switzerland 2015Javier Fandino, Serge Marbacher, Ali-Reza Fathi, Carl Muroi and Emanuela Keller (eds.)Neurovascular Events After Subarachnoid HemorrhageActa Neurochirurgica Supplement12010.1007/978-3-319-04981-6_26 Pharmacological Modulation of Spreading Depolarizations Renán Sánchez-Porras1 , Zelong Zheng1 and Oliver W. Sakowitz1 (1) Department of Neurosurgery, Heidelberg…
