Fig. 1 One-time pretreatment, 1 day prior to surgical brain injury: (a) postoperative brain water content; (b) modified 21-point sensorimotor score; (c) left-sided (contralateral to injured area) percentage of correct…
Fig. 1 LCN-2 protein levels in cortex (a) and hippocampus (b) after a sham operation (at day 1) or a TBI (at days 1, 3, and 7). Values are means ± SE,…
Fig. 1 Schematic, showing proposed mechanisms involving this preliminary investigation, directives of further study Fig. 2 OPN reduced brain edema. To determine the effects of OPN on BBB permeability, brain…
Fig. 1 Intracellular free zinc level in primary astrocytes. Primary astrocytes were treated with 0 or 100 μM zinc under 3 h hypoxia/12 h reoxygenation or 15 h normoxia condition….
Fig. 1 The traditional decompressive craniectomy. (a) Large right-sided fronto-temporal-parietal decompressive craniectomy is done and the bone is removed. Additional bone is removed for the subtemporal decompression. The dura is…
Fig. 1 Developmental milestone, measured by negative geotropism (seconds), 72 h after collagenase infusion; (asterisk) <0.05 compared with sham; (cross) <0.05 compared with GMH (vehicle); SEM standard error of the…
Treatments’ Surgery day Post-op day 1 Post-op day 2 6 h post–op “Early” start 6 h post–op 9 h post–op Every 4 h: 8 AM until 8 PM 8 AM…
Fig. 1 Example of swelling and infarct growth in a stroke patient. Baseline DWI (left panel) was compared with the co-registered follow-up DWI (middle panel) to assess the presence of…
Fig. 1 Thrombin activity following GMH, timed levels using standard assay Fig. 2 mTOR activity post-GMH; dose-response following PAR-1 and PAR-4 co- administration; 72 h after collagenase infusion; (asterisk) <0.05…
Fig. 1 COX-2 expression post-GMH; dose response following PAR-1 and PAR-4 co- administration; 72 h after collagenase infusion; (asterisk) <0.05 compared with sham; (cross) <0.05 compared with GMH (vehicle); SEM…
