Alcohol and Drug Abuse
Alcohol and Drug Abuse John C. M. Brust Introduction Worldwide, a variety of drugs are used recreationally, and they differ in their ability to produce either psychic dependence (compulsive drug-seeking…
Electrolyte, Sporadic Metabolic, and Endocrine Disorders
Electrolyte, Sporadic Metabolic, and Endocrine Disorders Giuseppe Gobbi Salvatore Grosso Gianna Bertani Antonella Pini Introduction Acute and chronic metabolic, electrolyte, and endocrine disorders may cause dysfunction or impairment of the…
Connective Tissue Diseases
Connective Tissue Diseases Barbara S. Koppel Introduction Seizures occur in several connective tissue diseases, most frequently systemic lupus erythematosus (SLE), and in forms of vasculitis that involve the brain. Often,…
Infection and Inflammatory Diseases
Infection and Inflammatory Diseases Oscar H. Del Brutto Introduction Infectious and inflammatory diseases of the central nervous system (CNS) cause a wide range of clinical manifestations, including decreased level of…
Neoplastic Diseases
Neoplastic Diseases Lawrence D. Recht Glantz Michael Introduction Seizures are frequently the first symptom in patients with brain tumors, and they represent an important cause of potentially preventable morbidity. They…
Cerebral Palsy
Cerebral Palsy John B. P. Stephenson Introduction Understanding epilepsy is a necessary part of the management of individuals with cerebral palsy.45 Epilepsy is common in all types of cerebral palsy…
Mitochondrial Diseases
Mitochondrial Diseases Michio Hirano Wolfram S. Kunz Salvatore DiMauro Introduction Since the initial discovery of mitochondrial DNA mutations in 1988, our understanding of the mitochondrial encephalomyopathies has advanced at an…
Inherited Metabolic Disorders
Inherited Metabolic Disorders Douglas R. Nordli Jr. Darryl C. De Vivo Introduction There are a wide variety of disorders of metabolism, approximately 50 of which are associated with seizures or…
Chromosomal Abnormalities
Chromosomal Abnormalities Renzo Guerrini Agatino Battaglia Romeo Carrozzo Giuseppe Gobbi Elena Parrini Tiziano Pramparo Orsatta Zuffardi Introduction About 30 years ago, chromosomal abnormalities, as detectable by classic cytogenetics, were estimated…
Malformations of Cortical Development
Malformations of Cortical Development Ruben I. Kuzniecky Graeme D. Jackson Introduction The development of the human brain is a long and complex process that begins with the induction of the…
