HIV, Fetal Alcohol and Drug Effects, and the Battered Child Pediatric AIDS and HIV Infection Incidence of neurologic abnormalities in HIV-infected cohorts has dropped from around 30% to <2% with…
Occupational and Environmental Neurotoxicology Table 167.1 lists selected neurotoxic syndromes. Table 167.1 Neurotoxic Syndromes Syndrome Agent Occupational or other exposure Acute Chronic Metals Arsenic Pesticides, pigments,…
Complications of Cancer Chemotherapy Tables 166.1, 166.2 list neurologic complications of cancer treatments. Table 166.1 Neurotoxicity of Antineoplastic Drugs Neurologic disorder Drug Peripheral neuropathy Carboplatin, cisplatin, cytarabine, docetaxel, etoposide, fludarabine,…
Iatrogenic Disease Selected adverse neurologic reactions due to drugs or diagnostic procedures listed in Table 165.1. Table 165.1 Adverse Neurologic Reactions Due to Drugs or Procedures for Diagnosis or Therapy…
Drug Dependence Psychic dependence (addiction): craving, drug-seeking behavior. Physical dependence: withdrawal symptoms and signs with abstinence. May occur separately or together. Addiction: psychic dependence. Selected classes of recreational drugs listed…
Alcoholism Ethanol-related deaths >100,000 each year; 5% of all deaths in United States. Problem drinkers: 7% of all adults, 19% of adolescents in United States addicted to ethanol or have…
Somatoform Disorders Somatoform disorders: conversion disorder, somatization disorder, pain disorder, hypochondriasis, body dysmorphic disorder. Somatizing disorders: besides somatoform disorders, also include malingering, factitious disorders, psychological factors affecting a medical condition…
Schizophrenia Abnormalities in perception of reality, form, and content of thoughts and speech, emotional deficits, leading to disturbed sense of self, social dysfunction, apathy, peculiar behavior. Symptom onset usually in…
Anxiety Disorders Overall prevalence 7% to 9%. F:M, 2 to 3:1. Panic Disorder Recurrent, unexpected panic attacks (Table 160.1), accompanied by persistent concerns about repeated attacks or significant behavior change…
Mood Disorders Major Depressive Disorder (MDD) Epidemiology 18.8 million people affected in U.S. in 1998. Affects 1 in 33 children, 1 in 8 adolescents. Lifetime prevalence in US 12% in…
