Neuropathic Pain
Neuropathic Pain Thomas H. Brannagan III INTRODUCTION In addition to numbness, neuropathic pain may result from damage to any level of the sensory pathway, from the small nerve fibers to…
Complex Regional Pain Syndrome
Complex Regional Pain Syndrome Michael L. Weinberger Thomas H. Brannagan III INTRODUCTION The complex regional pain syndrome has a long and changing history in medical practice. Veldman suggested that Ambrose…
Cranial Neuralgias and Facial Pain Disorders
Cranial Neuralgias and Facial Pain Disorders Marianna Shnayderman Yugrakh Denise E. Chou INTRODUCTION Facial pain can originate from various facial structures and includes pain due to disorders of the sinuses,…
Primary and Secondary Headache Syndromes
Primary and Secondary Headache Syndromes Peter J. Goadsby Denise E. Chou ANATOMY AND PHYSIOLOGY OF HEADACHE Headache is one of the most common symptoms evaluated by neurologists and bears a…
Vascular Dementias
Vascular Dementias Nikolaos Scarmeas INTRODUCTION During much of the 20th century, it was assumed that most dementia of the elderly was vascular in origin, an assumption challenged during the last…
Lewy Body Dementias
Lewy Body Dementias Sarah C. Janicki Karen S. Marder INTRODUCTION Dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD) share many clinical and pathologic features. They are therefore discussed…
Frontotemporal Dementia
Frontotemporal Dementia Edward D. Huey Stephanie Cosentino INTRODUCTION Frontotemporal dementia (FTD) is the most common clinical presentation of frontotemporal lobar degeneration (FTLD). Two main FTD phenotypes are seen. One form…
Alzheimer Disease
Alzheimer Disease Lawrence S. Honig Scott A. Small Richard Mayeux INTRODUCTION The most common dementia is Alzheimer disease. The disease was first named by Emil Kraepelin in 1910, after Alois…
Mild Cognitive Impairment
Mild Cognitive Impairment Lawrence S. Honig INTRODUCTION Cognitive complaints are common in the population. In many such cases, history and examination reveal significant impairment in more than one cognitive domain…
Central Nervous System Vasculitis
Central Nervous System Vasculitis Fawaz Al-Mufti Stephan A. Mayer INTRODUCTION Vasculitis affecting the central or peripheral nervous system often presents major diagnostic and therapeutic challenges for physicians because of its…
