© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_27 27. Quality of Life in Epilepsy Patsy J. Ramey1, Mohamad Z. Koubeissi1 and Nabil J. Azar1 (1) Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37212,…
© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_26 26. Procedures and Outcomes in Epilepsy Surgery Ronald P. Lesser1 (1) Department of Neurology, Johns Hopkins University School of Medicine, 600 North…
Generalized Convulsive Non-convulsive Focal Convulsive (epilepsia partialis continua) Non-convulsive Non-epileptic (“Pseudo-SE”) The task force on SE of the ILAE Commission on European Affairs has suggested a more exhaustive classification, as…
Domain Common measures—but not exhaustive list Skill All (most) ages Adult version Pediatric version Intellectual functioning Wechsler Abbreviated Scale of Intelligence-Second Edition (WASI-II) Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV)…
© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_20 20. Epilepsy Management in Special Populations Amir M. Arain1 (1) Vanderbilt University, A-0118 Medical Center North, Nashville, TN 37232, USA Amir M. Arain…
Animal model MES PTZ Kindling DBA/2 mice GAERS rats Human seizure/epilepsy type Generalized tonic-clonic seizures Generalized absence seizures Partial seizures (limbic) Generalized tonic-clonic, reflex seizures, SUDEP Generalized absence seizures Animal…
© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_18 18. Dietary Therapies Amy Kao1 (1) Center for Neurosciences and Behavioral Medicine, Children’s National Health System, 111 Michigan Ave NW, Washington,…
AED Felbamate Gabapentin Lamotrigine Topiramate Tiagabine Levetiracetam Protein bindinga Low Low Intermediate Low High Low Half-lifeb Intermediate Short Intermediate Intermediate Short Short Metabolism ~50% None Extensive ~30% Extensive ~30% Not…
AED Phenytoin Carbamazepine Oxcarbazepine MHD Phenobarbital Valproate Ethosuximide Protein bindinga High Intermediate Low Low High Low Half-lifeb Intermediate (can become long in toxicity) Intermediate Short Long Intermediate Long Metabolism Extensive,…
Syndrome Genetic test Inheritance Comment (a) Syndromes beginning in the 1st year of life Benign familial neonatal seizures KCNQ2 KCNQ3 AD M-channel subunit of voltage-gated potassium channel Seizure onset often…
