Figure 42-1 Histopathology of sural nerve: severe axonal degeneration. A, Teased fiber preparation demonstrates fulminant axonal degeneration. B, Longitudinal paraffin slides reacted to CD-68 show colocalization of macrophages with degenerating…
Figure 41-1 Intraoperative presentation of left poplitea and calf (asterisk). A large granuloma mass (arrowheads) expands the popliteal subfascial area and leads to compression of the peroneal nerve (arrow). After…
Figure 31-1 Sural nerve biopsy demonstrates amyloid deposition in epineurial blood vessels (Congo red). Figure 31-2 Gastrocnemius muscle biopsy demonstrates amyloid deposition in blood vessels (anti-transthyretin antibodies). Strength and sensation…
Figure 16-1 A lesion of the tibial nerve before its bifurcation into medial and lateral plantar divisions is seen on the noncontrast T1-weighted MRI image (arrow, right panel). The axial…
Figure 59-1 A, Transverse paraffin section stained with Luxol fast blue/periodic acid–Schiff demonstrating injury neuroma. Transverse paraffin sections stained with hematoxylin and eosin (B) demonstrating perivascular epineurial inflammatory cells with…
Figure 58-1 Sural nerve biopsy demonstrates severe axonal loss with perivascular lymphocytic infiltration (Epon) in the epineurium (left) and CD79a positivity of lymphocytes (right). CONCLUSIONS The exact incidence of extrahepatic…
A key pathologic feature characteristic of ALS neurons is the presence of intracytoplasmic deposits of ubiquinated immunoreactive inclusions, recently shown to be the protein TDP-43, a nuclear factor about which…
Figure 55-1 Serial longitudinal paraffin sections show congophilic deposits surrounding endoneurial microvessels (Congo red stain, upper left) and apple green birefringence under polarized light (upper right). The section in the…
Sensory deficit Sensory deficit Sensory dissociation Common Rare Autonomic dysfunction in early stages Severe with ADL disturbance Mild without ADL disturbance Cardiac involvement Atrioventricular conduction block Cardiomegaly Anticipation of age…
Figure 54-1 The structure of infliximab. (Adapted from Knight DM, Trinh H, Le J, Siegel S, Shealy D, McDonough M, Scallon B, et al. Construction and initial characterization of a…
