History of Astrocytes

Sep 11, 2017 by in NEUROLOGY Comments Off on History of Astrocytes

Chapter 1 History of Astrocytes Abstract In this introduction to the history of astrocytes, we (1) contextualize the evolution of the concept of neuroglia within the development of cell theory…

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Types of Epilepsy

Sep 11, 2017 by in NEUROLOGY Comments Off on Types of Epilepsy

Chapter 4 Types of Epilepsy Abstract Epilepsy, affecting at least 2% of the population, comprises a group of disorders of the brain characterized by the periodic and unpredictable occurrence of…

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Neuropathology of Human Epilepsy

Sep 11, 2017 by in NEUROLOGY Comments Off on Neuropathology of Human Epilepsy

Chapter 5 Neuropathology of Human Epilepsy Abstract In this chapter, we briefly review salient features of the pathology of human focal epilepsies. We present human histopathological data and classification of…

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Adenosine Metabolism

Sep 11, 2017 by in NEUROLOGY Comments Off on Adenosine Metabolism

Chapter 10 Adenosine Metabolism Abstract Adenosine is a neuromodulator that plays a role in energy metabolism, cellular communication, and DNA methylation. Purinergic signaling can be carried out by two different…

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Glutamate Metabolism

Sep 11, 2017 by in NEUROLOGY Comments Off on Glutamate Metabolism

Chapter 9 Glutamate Metabolism Abstract The majority of energy consumed by the brain is used to maintain membrane potentials of neurons after action potentials are fired. Glutamate, the main neurotransmitter…

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Potassium Channels

Sep 11, 2017 by in NEUROLOGY Comments Off on Potassium Channels

Chapter 7 Potassium Channels Abstract Astrocytes play a critical role in maintaining extracellular K+ homeostasis. Since neuronal activity is accompanied by efflux of K+ from neurons into the extracellular space,…

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