20 Indocyanine Green and Cerebral Revascularization Lars Wessels, Nils Hecht, and Peter Vajkoczy AbstractMaintenance of cerebral blood flow is essential to prevent cerebral ischemia. In 10% of ischemic stroke patients,…
9 5-Aminolevulinic Acid Utility in Pediatric Brain Tumors, Other Adult Brain Tumors, and Photodynamic Therapy Nikita Lakomkin, Isabelle M. Germano, and Constantinos G. Hadjipanayis AbstractThe use of 5-aminolevulinic acid (5-ALA)…
15 Confocal Endomicroscopy Christina E. Sarris and Nader Sanai AbstractFluorescence image-guided surgery is rapidly demonstrating its ability to improve brain tumor resections. However, there are still a number of limitations…
1 Current Fluorescence-Guided Neurosurgery and Moving Forward Remi A. Kessler, Frank J. Yuk, and Constantinos G. Hadjipanayis AbstractThis introductory chapter provides a current overview of fluorescence-guided neurosurgery and includes future…
11 Fluorescein and High-Grade Gliomas Justin A. Neira, Randy S. D’Amico, and Jeffrey N. Bruce AbstractAs use of 5-aminolevulenic acid (5-ALA) in guiding resection of malignant glioma has been popularized,…
5 5-Aminolevulinic Acid in Low-Grade Gliomas Georg Widhalm, Mitchel S. Berger, and Johannes Wölfer Abstract5-aminolevulinic acid (5-ALA)-induced tumor fluorescence represents a powerful tool to optimize the resection of high-grade gliomas…
2 Designing and Reporting Studies on Intraoperative Tissue Imaging in the Brain Walter Stummer AbstractIntraoperative optical tissue imaging for identifying tumor-infiltrated brain is a rapidly expanding field. Clinically, intraoperative tissue…
10 Fluorescein-Guided Tumor Resection in Neurosurgical Oncology Joseph F. Georges and Peter Nakaji AbstractThis chapter reviews fluorescein-guided resection of intracranial neoplasms such as gliomas, meningiomas, and metastases. Fluorescein’s utility in…
7 5-Aminolevulinic Acid and Brain Metastases Marcel A. Kamp, Marion Rapp, Jan Frederick Cornelius, Hans-Jakob Steiger, and Michael Sabel AbstractCerebral metastases are one of the most common intracerebral neoplasms. It…
