13 Cancer-Targeted Alkylphosphocholine Analogs for Intraoperative Visualization Ray R. Zhang, Paul A. Clark, Jamey P. Weichert, and John S. Kuo AbstractWithin the last decade, several clinical trials pairing targeted fluorophores…
14 Tozuleristide Fluorescence-Guided Surgery of Brain Tumors Harish Babu, Dennis M. Miller, Julia E. Parrish-Novak, David Scott Kittle, Pramod Butte, and Adam N. Mamelak AbstractTozuleristide is a near-infrared (NIR) tumor-targeting…
19 Indocyanine Green Videoangiography and Arteriovenous Malformations Justin R. Mascitelli, Jan-Karl Burkhardt, and Michael T. Lawton AbstractIndocyanine green videoangiography (ICG-VA) is a useful intraoperative tool for outlining the anatomy and…
17 Raman Spectroscopy and Brain Tumors Todd C. Hollon, Steven N. Kalkanis, and Daniel A. Orringer AbstractLabel-free imaging techniques rely on the intrinsic biochemical properties of tissues to generate image…
20 Indocyanine Green and Cerebral Revascularization Lars Wessels, Nils Hecht, and Peter Vajkoczy AbstractMaintenance of cerebral blood flow is essential to prevent cerebral ischemia. In 10% of ischemic stroke patients,…
9 5-Aminolevulinic Acid Utility in Pediatric Brain Tumors, Other Adult Brain Tumors, and Photodynamic Therapy Nikita Lakomkin, Isabelle M. Germano, and Constantinos G. Hadjipanayis AbstractThe use of 5-aminolevulinic acid (5-ALA)…
15 Confocal Endomicroscopy Christina E. Sarris and Nader Sanai AbstractFluorescence image-guided surgery is rapidly demonstrating its ability to improve brain tumor resections. However, there are still a number of limitations…
1 Current Fluorescence-Guided Neurosurgery and Moving Forward Remi A. Kessler, Frank J. Yuk, and Constantinos G. Hadjipanayis AbstractThis introductory chapter provides a current overview of fluorescence-guided neurosurgery and includes future…
11 Fluorescein and High-Grade Gliomas Justin A. Neira, Randy S. D’Amico, and Jeffrey N. Bruce AbstractAs use of 5-aminolevulenic acid (5-ALA) in guiding resection of malignant glioma has been popularized,…
5 5-Aminolevulinic Acid in Low-Grade Gliomas Georg Widhalm, Mitchel S. Berger, and Johannes Wölfer Abstract5-aminolevulinic acid (5-ALA)-induced tumor fluorescence represents a powerful tool to optimize the resection of high-grade gliomas…
