INTRODUCTION Print Section Listen Neurologic infections can be classified by clinical syndrome/localization (e.g., meningitis vs encephalitis vs myelitis vs radiculitis) and by the type of infection (e.g., viral, bacterial, tuberculous,…
INTRODUCTION Print Section Listen The nervous system can be affected in several ways in patients with neoplastic disease: Directly due to primary nervous system tumors or metastases to nervous system…
APPROACH TO ALTERED COGNITION Print Section Listen When assessing patients with acute or chronic changes in cognition, two interrelated questions should be pursued during the history and examination: Is the…
INTRODUCTION Print Section Listen At the neuromuscular junction motor neurons release acetylcholine that binds to acetylcholine receptors on the postsynaptic muscle fibers, causing them to contract. Diseases of the neuromuscular…
INTRODUCTION TO MOVEMENT DISORDERS Print Section Listen In most realms of neurologic disease, localization is the first step toward differential diagnosis. In assessing movement disorders, however, the first step is…
CAUSES OF MUSCLE DISEASE Print Section Listen Muscle disease can be caused by: Inflammatory diseases: polymyositis, dermatomyositis, inclusion body myositis, immune-mediated necrotizing myopathy Medications: most commonly statins and corticosteroids, but…
LEUKODYSTROPHIES Print Section Listen The leukodystrophies are diseases that affect the white matter of the CNS (Table 31–1). These diseases can begin in infancy, childhood, or adulthood. Infantile-onset leukodystrophies are…
INCREASED INTRACRANIAL PRESSURE (INTRACRANIAL HYPERTENSION) Print Section Listen General Principles of Intracranial Pressure Intracranial Contents Contributing to Intracranial Volume and Pressure The skull contains three components that contribute to intracranial…
OVERVIEW OF MOTOR NEURON DISEASE Print Section Listen This chapter discusses a group of diseases that affect motor neurons in isolation, collectively referred to as motor neuron disease. Motor neuron…
