Control of Neuronal Excitability
Control of Neuronal Excitability Uwe Heinemann Istvan Mody Yoel Yaari Introduction The behavior of nerve cells is determined by ionic channels. These are transmembrane proteins with a pore that permits…
NEUROLOGY
Overview: The Neurobiology of Epilepsy
Overview: The Neurobiology of Epilepsy Marc A. Dichter Introduction The epilepsies are a complex group of disorders whose common feature is a tendency for hyperexcitability to develop in one or…
Genetic Counseling
Genetic Counseling Frances Elmslie Introduction Genetic counseling has become an integral component of care of many conditions that display mendelian inheritance, and increasingly those that show complex inheritance, such as…
Genetics of Epilepsy Syndromes
Genetics of Epilepsy Syndromes Ortrud K. Steinlein Introduction The term epilepsy describes a heterogeneous group of disorders, with a lifetime cumulative incidence of 3%. There are disorders in which seizures…
Genetic Diseases Associated with Epilepsy
Genetic Diseases Associated with Epilepsy Joshua L. Bonkowsky Martha A. Nance W. Allen Hauser V. Elving Anderson Introduction Genetics has become increasingly important for understanding epilepsy. Since the advent of…
EEG Traits
EEG Traits Timothy A. Pedley Introduction At the most fundamental level, cortical excitability and electrical organization are genetically specified, and it is probable that each identifiable electroencephalographic (EEG) pattern is…
Neuropathology of Developmental Disorders Associated with Epilepsy
Neuropathology of Developmental Disorders Associated with Epilepsy Harry V. Vinters Noriko Salamon Hajime Miyata Negar Khanlou Gary W. Mathern Introduction Structural lesions associated with epilepsy can be categorized into the…
Genetic Epidemiology
Genetic Epidemiology Ruth Ottman Melodie R. Winawer Introduction A genetic contribution to the epilepsies has been suspected for centuries, but until recently, progress in elucidating the specific genetic influences was…
Hippocampal Sclerosis
Hippocampal Sclerosis Gary W. Mathern Charles L. Wilson Heinz Beck Introduction Hippocampal sclerosis is the most frequent pathologic finding in patients with temporal lobe epilepsy undergoing resective neurosurgery, and its…
General Neuropathology of Epilepsy
General Neuropathology of Epilepsy Michael A. Farrell Ingmar Blümcke Negar Khanlou Harry V. Vinters Introduction The history of the study of structural brain changes in patients with intractable epilepsy is…
