Stereotactic Radiosurgery
14 Stereotactic Radiosurgery Ricky Medel, Brian Williams, and Jason P. Sheehan Tumors in and around the sella turcica represent some of the most challenging clinical entities that clinicians have dealt with…
NEUROSURGERY
Surgical Treatment of Pituitary Adenomas
6 Surgical Treatment of Pituitary Adenomas Soriya Motivala, Yakov Gologorsky, Joshua Bederson, and Kalmon D. Post Pituitary adenomas are epithelial tumors arising from the adenohypophysis that can manifest with neurologic symptoms…
Chemotherapy Options for Sellar and Parasellar Tumors
16 Chemotherapy Options for Sellar and Parasellar Tumors Arnaldo Neves Da Silva and David Schiff Among the sellar and parasellar tumors that may be amenable to treatment with chemotherapy are pituitary…
Introduction and Historical Perspective
1 Introduction and Historical Perspective Edward R. Laws Jr. and Zachary N. Litvack “As is true of all difficult operative procedures, the performance becomes progressively simplified by the combined suggestion and…
Medical Evaluation and Management
4 Medical Evaluation and Management Mary Lee Vance Of the many types of lesions that occur in the sella or parasellar region, a pituitary adenoma is the most common. All lesions…
Extracellular Signals Controlling Neuroblast Migration in the Postnatal Brain
Fig. 9.1 Neurogenesis in the SVZ. (a) Schematic brain sagittal section showing the two main neurogenic niches in the postnatal brain, the dentate gyrus of the hippocampus and the SVZ…
Microtubules and Neurodevelopmental Disease: The Movers and the Makers
Fig. 5.1 Microtubule biology and cellular function. (a) Tubulin heterodimers are the basic building units of microtubules. Both isoforms can bind to a guanidine nucleotide. Whereas α-tubulin cannot hydrolyze and…
Novel Functions of Core Cell Cycle Regulators in Neuronal Migration
Fig. 4.1 Cortical layering process in mouse embryos. Half coronal section through the forebrain of an E14.5 mouse embryo (upper left scheme). Successive waves of post-mitotic projection neurons are generated…
Molecular Pathways Controlling the Sequential Steps of Cortical Projection Neuron Migration
Fig. 1.1 Developmental sequence of inside-out cortical layer assembly. During cortical layer formation, earlier born neurons occupy lower layers and later born neurons progressively occupy upper layers. In the developing…
The PAR Polarity Complex and Cerebellar Granule Neuron Migration
Fig. 7.1 Germinal zone migration in the developing cerebellum. (a) Cerebellar granule neuron precursors (cGNPs) migrate tangentially (horizontal arrows) within the External Granule Layer (EGL). They then transition to a…
