Spinal Synaptic Plasticity in Chronic Pain

Mar 11, 2017 by in NEUROSURGERY Comments Off on Spinal Synaptic Plasticity in Chronic Pain

Fig. 31.1 Excitatory synaptic transmission in the dorsal horn. When an impulse is transmitted to central terminals of afferent fibers, excitatory neurotransmitters are released. Glutamate and substance P act at…

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Evaluation of Pain with Functional Neuroimaging

Mar 11, 2017 by in NEUROSURGERY Comments Off on Evaluation of Pain with Functional Neuroimaging

  Target Spatial resolution (mm) Temporal resolution (S) EEG/MEG Neuronal current 10 0.001 fMRI Regional changes in blood flow 4–5 1–10 PET Oxygen consumption, glucose metabolism etc. 5–10 30–1,000 SPECT…

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Blockade of Interleukin-6 Effects on Cytokine Profiles and Macrophage Activation After Spinal Cord Injury in Mice

Mar 11, 2017 by in NEUROSURGERY Comments Off on Blockade of Interleukin-6 Effects on Cytokine Profiles and Macrophage Activation After Spinal Cord Injury in Mice

Fig. 17.1 Histological and behavioral evaluation after anti-interleukin (IL)-6 receptor (MR16-1) treatment. Luxol fast blue (LFB) stained axial sections at the injury epicenter (42 days post-injury) showed remarkable reduction in…

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