Figure 8.1 The complexity of clinicopathologic relationships along the frontotemporal lobar degeneration (FTLD) spectrum. The major clinical syndromes along the FTLD spectrum are shown in the top row of the…
MAPT (tau)GRN (progranulin)TDP-43TauOthersVCPCHMP2BTARDBP (TDP-43)FUSFUS C9ORF72 C9ORF72 is the newest addition to the roster of causative molecules in FTD. In 2011, expansions of a GGGGCC hexanucleotide repeat in C9orf72 were found…
Figure 9.1 The INECO Frontal Screening (IFS) [39]. Classical executive function tests The most frequent classical executive function tests used in patients with bvFTD are: the backward digit span [5],…
Figure 12.1 Pedigree for Case 1. The genetic counselor and neurologist meet with Mr. and Mrs. G. for the disclosure of the genetic testing results, which are positive for a…
Figure 6.1 Calculation of verbal fluency index. The verbal fluency index (Vfi) is calculated using a motor control condition in which after the participant has generated words in the given…
Figure 19.1 The family’s journey to a diagnosis of FTD. Stage I. Something is wrong Whether initial symptoms are word-finding difficulties, a change in energy level, a few lapses in…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 18 Pharmacologic therapy for FTD and related disordersCurrent options and future strategies Richard M. Tsai and Adam L. Boxer Hodges’ Frontotemporal Dementia, Second Edition, ed….
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 17 Practical management of frontotemporal dementia Edward D. Huey and Masood Manoochehri Hodges’ Frontotemporal Dementia, Second Edition, ed. Bradford C. Dickerson. Published by Cambridge University…
Figure 14.1 Clinical characteristics associated with the major FTLD genes GRN, C9orf72, and MAPT. Shaded areas represent interquartile distribution of onset age (y-axis) and FTLD subtype (x-axis). Vertical lines represent…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 11 Cerebrospinal fluid biomarkers of frontotemporal lobar degeneration Nicolaas A. Verwey, Yolande A. L. Pijnenburg, and Philip Scheltens Hodges’ Frontotemporal Dementia, Second Edition, ed. Bradford…
