Figure 38-1 Sural nerve features. A, Considerable reduction in myelinated nerve fiber density. Few axons with disproportionately thin myelin sheaths, minor onion bulb formation (black arrows). Sporadic nerve fibers with…
CONCLUSION CMT-4C is an extremely rare autosomal recessive demyelinating motor sensory neuropathy. Thus far, a little more than 60 cases have been reported in the literature.3–5 In addition to the…
Figure 33-1 Sural nerve biopsy. Paraffin-embedded longitudinal section stained with an antitransthyretin antibody. Amorphous deposits labeled by the antibody are present in the endoneurium, sometimes in perivascular regions (arrow) or…
Figure 32-1 Amyloid depositions (arrows) in endoneurium and vessel walls illustrated by Congo-red stain (top left) showing apple green birefringence under polarized light (top right), H&E stain (bottom left), methylviolet…
Figure 18-1 Right radial motor nerve conduction studies, demonstrating conduction block when the nerve was stimulated at the axilla and Erb’s point, recording over the extensor digitorum communis. “Sp. Grove”…
Figure 20-1 Cross-sectional ultrasound image taken at the fibular head. The fibular head (white arrow). Hypoechogenic cyst (blue arrow). The peroneal nerve is not readily identified in this image. Figure…
Figure 11-1 3-Tesla MRI of the lumbosacral plexus. Top: oblique coronal T2-weighted fast-spin echo sequence with fat saturation showing enlargement and prominent hyperintensity in the left sciatic nerve (long arrow),…
Figure 25-1 Electron micrograph of a radial sensory nerve with numerous macrophages and Schwann cells containing non–membrane-bound lipid vacuoles (arrows). CONCLUSIONS Tangier disease is a condition characterized by severe deficiency…
Figure 13-1 Magnetic resonance imaging scan of the lumbosacral spine. Top: Midsagittal view of lumbosacral spine with T2 (left) and T1 with gadolinium contrast (right) sequences. Arrows highlight enlarged roots…
Figure 23-1 A, Photomicrograph of a sural nerve frozen section immunoreacted with CD 68 to visualize macrophages. Note infiltration of the blood vessel wall (macrophages stained in brown) and subtotal…
