Fig. 6.1 Micrograph of an early outgrowth colony forming unit—endothelial cell (CFU-EC) isolated from an ischemic stroke patient in a phase-contrast microscope (×100). A CFU-EC consisted of a central cluster…
Fig. 10.1 Mechanisms regulating cellular changes in the two neurogenic compartments following traumatic brain injury (TBI). Similarities and differences exist between TBI-induced responses in the SVZ (A-D) and dentate gyrus…
5.2.1 Hematopoieitic Stem Cells The initial use of UCB for treatment of hematopoietic disorders was based on the ability of HSCs in the UCB to reconstitute the immune system and…
Fig. 7.1 An overview of isolation methods and characteristics of early and late EPCs 7.2.4 Classification of EPCs According to their culture characteristics and functions, circulation EPCs can be classified…
Fig. 2.1 Schematic diagram of NSC/NPC behavior in the RMS. a NSC/NPC behavior in the RMS of intact brain. Note that NSCs/NPCs in the RMS are divided into two sub-types:…
Fig. 4.1 BMSC therapy induces neurorestorative effects post stroke Fig. 4.2 The various aspects of neurorestoration that are targeted by cell therapy to improve neurological recovery post stroke 4.3.1 BMSC…
© Springer International Publishing Switzerland 2015Li-Ru Zhao and John H. Zhang (eds.)Cellular Therapy for Stroke and CNS InjuriesSpringer Series in Translational Stroke Research10.1007/978-3-319-11481-1_3 3. The Role of Endogenous Neural Stem Cells in Stroke Qichuan ZhuGe1, 3 ,…
Fig. 15.1 Pathophysiological time course following TBI. (Reproduced from Walker et al. [32]) Extracellular matrix destabilization occurs along with cellular dysfunction. The concentration of several matrix metalloproteinase (MMP) proteins are…
Study reference/principal investigator Study title Route Cell type/source Recipient species Therapeutic window Dose Outcome measures Follow-up/outcome measurements Results summary [10] Treatment of stroke in rat with intracarotid administration of marrow…
Study Phase Type of cells Route of injection Time after stroke Sample size Results Kondziolka et al., Neurology 2000 I Cultured neuronal cells differentiated from a human teratocarcinoma cell line…
