Fig. 2.1 Intracranial hemorrhage in cerebral amyloid angiopathy. Axial and coronal T2- and axial T1-weighted images (a–c) demonstrate a large right intracranial hemorrhage with perilesional edema. Axial T2*-weighted gradient-echo images,…
Fig. 3.1 Age- and sex-adjusted survival of patients with primary central nervous system vasculitis (PCNSV) versus estimated survival of the US white population (p < 0.001) Patients with several bilaterally affected large…
WHO class Definition Grade Mitosis Ki67% I NET G1 <2 ≤2 II NET G2 2–20 3–20 III NEC G3 >20 >20 IV MANEC nd nd nd V Hyperplasia/dysplasia na na…
Fig. 19.1 Multihormonal microadenoma in the MEN1 pancreas immunostained for (a) glucagon and (b) pancreatic polypeptide In MEN1 patients, all somatic cells harbor a heterozygous germline mutation of the MEN1…
Fig. 2.1 Functioning PanNETs US. Small insulinoma of pancreatic body. Axial scan: hypoechoic mass (calipers) with smooth margins and about 1 cm in diameter, located at the anterior border of…
Fig. 13.1 ACTH-producing PanNET. The tumor cells grow in solid sheets (H&E, ×200) Fig. 13.2 ACTH-producing PanNET with a trabecular pattern of growth and moderate stromal fibrosis (H&E, ×200) Fig….
Fig. 5.1 A 35-year-old female with weight loss and jaundice. Initial investigations revealed a 7 cm mass in the pancreatic head. An endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) with rapid…
Fig. 18.1 Mixed adenoneuroendocrine carcinoma (MANEC) of the pancreas. (a) In the left half of the image, the pancreatic ductal adenocarcinoma component is composed of well-differentiated glandular structures within desmoplastic…
Fig. 17.1 Small cell carcinomas are characterized by loosely arranged sheets of small cells with a high N:C ratio, hyperchromatic and finely granular chromatin, inconspicuous nucleoli, and nuclear molding. High…
