Movement Disorders in Children
Childhood movement disorders are both similar and distinct from movement disorders in adulthood. While the two overlap in their definitions of specific movements, this chapter will serve to highlight the…
Mitochondria in Movement Disorders
Related posts: Neurologic Aspects of Wilson’s Disease: Clinical Manifestations and Treatment Considerations Catatonia Treatment of Dystonia Cell-Based Therapy for Parkinson’s Disease Ballism Botulinum Toxin in Movement Disorders
Disorders of Gait
INTRODUCTION Gait, the art and manner of walking, is defined as a learned complex motor skill that facilitates locomotion. Humans have used the bipedal form of locomotion for more than…
Neurodegeneration with Brain Iron Accumulation
SUMMARY Syndromes with neurodegeneration with brain iron accumulation (NBIA) are a group of neurodegenerative disorders characterized by abnormalities in brain iron metabolism with excess iron accumulation in the globus pallidus…
Peripherally Induced Movement Disorders
INTRODUCTION There are many case reports and case series describing the development of a movement disorder (MD) following peripheral trauma (see for a review (1)). These so-called peripherally induced MDs…
Trophic Factor and Gene Therapies for Parkinson’s Disease
INTRODUCTION Parkinson disease (PD) is a degenerative and progressive disorder characterized by the degeneration of the nigrostriatal pathway projecting to the striatum. All commonly employed therapies in PD have been…
Surgery for Hyperkinetic Movement Disorders
TREMOR Tremor, of different etiologies, can be a very disabling symptom when becomes refractory to medical treatment. In such circumstances, surgical therapies should be advised. Surgical therapies include stereotactic and…
Cell-Based Therapy for Parkinson’s Disease
INTRODUCTION Despite its complex phenotypic heterogeneity, all cases of Parkinson’s disease (PD) have in common two pathologic hallmarks: degeneration of the nigrostriatal dopaminergic system and accumulation of the protein α-synuclein…
Genetics of Parkinson’s Disease
INTRODUCTION Parkinson’s disease (PD) is the second most frequent neurodegenerative disorder, affecting about 2% of individuals over the age of 65. Clinically, PD patients present with the cardinal motor symptoms…
Paraneoplastic and Immunologically Mediated Movement Disorders
Related posts: Neurologic Aspects of Wilson’s Disease: Clinical Manifestations and Treatment Considerations Catatonia Treatment of Dystonia Disorders of Gait Ballism Botulinum Toxin in Movement Disorders
