Encephalopathic Generalized Epilepsy and Lennox–Gastaut Syndrome
Figure 20.1. Diffuse slow spike-and-wave complexes on interictal EEG in a 7-year-old with LGS. The finding of SSW on the EEG is an ominous finding. Drug-resistant generalized epilepsy is present…
Continuous Spike-and-Wave During Sleep Including Landau–Kleffner Syndrome
Figure 21.1. Graphic representation of continuous spike-and-wave during sleep evolution over time. The age of clinical events varies in individual patients but tends to peak at approximately the displayed ages….
Strategies and Indications for Evaluation with Invasive Electrodes
Figure 81.1. Intraoperative aspect of SDG/depth electrode implantation in a patient with extratemporal epilepsy and nonlesional MRI. The picture shows a large right-sided temporofrontal craniotomy with placement of SDGs at…
Phenobarbital and Primidone
Figure 60.1. Structural formulas of PRM and its main metabolites. CHEMISTRY AND MECHANISM OF ACTION Phenobarbital Chemically, PB is 5-ethyl-5-phenylbarbituric acid (see Fig. 60.1). The molecular weight is 232.23, and…
Psychiatric Comorbidity of Epilepsy
For those with peri-ictal depression, improved seizure control may be a sufficient treatment. For patients with resistant peri-ictal depression, interictal MDD, persistent depressive disorder, or IDD, antidepressant treatment is indicated….
