A Case of Autoimmune Autonomic Ganglionopathy
Figure 64-1 Cardiovascular autonomic testing in the patient with AAG (left panels) and a normal control (right panels). Heart rate is depicted in green, blood pressure in brown, and respiratory…
Neurogastrointestinal Encephalomyopathy: A Demyelinating Disorder of Nerves
Figure 36-1 A 35-year-old man is shown. A, Note the thin body habitus and musculature build of the patient. B, Ptosis of the right eye and a left and evident…
The AAN Case Definition for Distal Symmetric Polyneuropathy
Table 74-2 Estimated likelihood of distal symmetric polyneuropathy for case definitions that include only symptoms and signs: recommendations for field or epidemiologic studies In order to clarify the case definition,…
Characteristic Sudomotor Abnormalities in Lepromatous Leprosy
Figure 68-1 First thermoregulatory sweat test (yellow areas indicate anhidrosis): impaired sweating of the right forearm, left greater than right leg, bilateral thighs, dorsum of the feet, and forehead (left);…
Genes and Inherited Neuropathies
Figure 78-1 The relationships of inherited neuropathies to each other and other syndromes. These Venn diagrams depict that dominantly inherited neuropathies can be separated into demyelinating and axonal forms (A);…
Schwann Cell Investment of Unmyelinated Nerve Fiber
Figure 73-1 A teased unmyelinated fiber cluster (UFC) stained with cresyl violet. The preparation allows linear measurement of internuclear lengths (upper panel). Transverse sections of a teased UFC under light…
Corneal Lattice Dystrophy, Facial Weakness and Sensorimotor Polyneuropathy—Gelsolin Amyloidosis
Figure 34-1 Symmetric facial weakness and skin laxity. Her family history was significant for multiple similarly affected family members shown in the pedigree (Fig. 34-2). Her position in the pedigree…
A Distinct Neuropathy with Hypotonia, Kinky Hair, and Axonal Spheroids—Giant Axonal Neuropathy
Figure 28-1 The patient showing the kinky hair described in text. Nerve conduction studies demonstrated absent upper extremity sensory responses. The sural response was low normal amplitude (8 μV) with…
Role of High-Resolution Imaging in Patients with Painful Lumbosacral Plexopathy
Figure 79-1 Pelvic magnetic resonance imaging scan with and without gadolinium. A, Oblique coronal T1-weighted image (T1WI) demonstrates isointense enlargement of the right S1 and S2 nerve roots. B, Fat-saturated…
Amyloidosis Typing Based on Laser Microdissection and Mass Spectrometry of Paraffin-Embedded Tissue Biopsies
Figure 80-1 Illustration of the process of amyloid specific microdissection. A, Peripheral nerve biopsy stained with Congo red indicating amyloid positive regions (arrows). B, Amyloid-positive areas are selected and outlined…
