CHAPTER 71 How Far Have We Come in Prevention and Treatment of Peripheral Neuropathy? Peter J. Dyck, MD INTRODUCTION At a recent conference assessing “Advances in understanding and treating neuropathy”…
Figure 46-1 Higher power view of sural nerve biopsy, transverse semithin section, stained with toluidine blue demonstrating loss of myelinated axons, thinly myelinated axons, a circumferentially oriented Schwann cell profile…
Figure 17-1 The serial nerve conduction studies of the left peroneal motor nerve (A) and the right tibial motor nerve (B) in acute stage: upper trace, the initial study which…
Autoantibodies to gangliosides By an enzyme-linked immunosorbent assay (ELISA) as described elsewhere,1 IgM and IgG antibodies against ganglioside GM1, GM1b, GD1a, GalNAc-GD1a, GD1b, GT1a, or GQ1b were investigated in serum…
Figure 42-1 Histopathology of sural nerve: severe axonal degeneration. A, Teased fiber preparation demonstrates fulminant axonal degeneration. B, Longitudinal paraffin slides reacted to CD-68 show colocalization of macrophages with degenerating…
Figure 41-1 Intraoperative presentation of left poplitea and calf (asterisk). A large granuloma mass (arrowheads) expands the popliteal subfascial area and leads to compression of the peroneal nerve (arrow). After…
Figure 31-1 Sural nerve biopsy demonstrates amyloid deposition in epineurial blood vessels (Congo red). Figure 31-2 Gastrocnemius muscle biopsy demonstrates amyloid deposition in blood vessels (anti-transthyretin antibodies). Strength and sensation…
Figure 16-1 A lesion of the tibial nerve before its bifurcation into medial and lateral plantar divisions is seen on the noncontrast T1-weighted MRI image (arrow, right panel). The axial…
Figure 58-1 Sural nerve biopsy demonstrates severe axonal loss with perivascular lymphocytic infiltration (Epon) in the epineurium (left) and CD79a positivity of lymphocytes (right). CONCLUSIONS The exact incidence of extrahepatic…
Figure 59-1 A, Transverse paraffin section stained with Luxol fast blue/periodic acid–Schiff demonstrating injury neuroma. Transverse paraffin sections stained with hematoxylin and eosin (B) demonstrating perivascular epineurial inflammatory cells with…
